Gene study pinpoints superbug link between people and animals
Scientists have shed light on how a major cause of human and animal disease can jump between species, by studying its genes.
The findings reveal fresh insights into how new disease-causing strains of the bacteria – called Staphylococcus aureus – emerge. Experts say the research could help improve the use of antibiotics and design better strategies for limiting the spread of disease.
S. aureus bacteria usually live harmlessly in our noses. If the bacteria get into a cut, however, they can cause infections that, in rare instances, can be deadly.
Antibiotic resistant strains of the bacteria, such as MRSA, are a major cause of hospital acquired infections.
The bacteria is also a major burden for the agricultural industry as it causes diseases such as mastitis in cows and skeletal infections in broiler chickens.
A team led by the University of Edinburgh’s Roslin Institute analysed the entire genetic make-up of more than 800 strains of S. aureus that were isolated from people and animals.
The researchers sought to investigate the evolutionary history of the bacteria and key events that had allowed it to jump between species.
They found that humans were the likely original host for the bacteria. The first strains capable of infecting livestock emerged around the time animals were first domesticated for farming.
- £12 million in grants to tackle superbugs in a global context
- UK government commits over £30 million of funding to tackle antimicrobial resistance
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