As a board or panel member, you will use your expertise and experience to help MRC invest in high-quality and impactful research, innovation and training as well as providing input into our strategy, including through interactions with other boards and panels and MRC’s advisory structures.
As it is not possible for individuals to provide in-depth expertise across all specialities, members will work collectively through open and objective discussions to provide advice across the board or panel remit, sharing responsibility for judgments and recommendations.
MCMB is responsible for MRC’s investments seeking to understand the molecular and cellular mechanisms that underpin complex biological function in human health and disease and supporting the early translation of knowledge towards new diagnosis and treatment.
We have particular interest in the integrated understanding of disease, the link with external exposures and research maximising opportunities at the life-physical science interface.
We invite applications from clinical and non-clinical researchers and from industry. For further information, refer to the remit of the Molecular and Cellular Medicine Board.
Areas of expertise
Cell biology
Broad expertise is sought in cell biology relevant to human health and disease, including in the areas of membrane trafficking and intracellular compartments. Other areas of interest include ribonucleic acid biology, metabolomics and post-transcriptional regulation or modification.
Applicants with expertise in biophysics or at the physical science interface, and in advanced imaging are particularly encouraged, along with strong commitment to integrating across biological scales which may include expertise in model systems.
Biomedical informatics
Expertise in biomedical informatics or computational biology. Applicants should have a strong track record in applying informatics and computational approaches to understanding underlying biology and mechanisms of human disease, from the cellular level through to the whole disease phenotype. Expertise in analysing and interpreting a wide range of ‘omics data would be an advantage.
Haematology, blood cell biology and development
Expertise is sought in haematopoiesis, haematopoietic stem cell biology and haematological dysfunction or disease.
Stem cells and regenerative medicine
Expertise in stem cell biology, tissue repair and regenerative biology or medicine. Experience of translational approaches to regenerative medicine or advanced therapeutics would be an advantage.
Therapeutic development
Expertise in early phase therapeutic development, including target discovery and validation. Expertise in advanced treatments would be desirable and industry representatives are particularly welcome.
Oncology
Expertise in underpinning cancer cell biology, pathological molecular mechanisms, and tumour microenvironment. This could include, but is not limited to:
- complex cancer models or model organisms
- cancer epidemiology or patient stratification
- expertise in DNA damage pathways
- translational oncology research
Expertise in host-microbe interactions would be an advantage. Experience of experimental medicine or translational approaches would also be an advantage, including therapeutic relevance of preclinical models.
We are particularly interested to receive applications from those with expertise in the use of quantitative analytical tools, multi-dimensional data and systems approaches to understand complex and dynamic biology.
We are committed to reproducibility in research so applicants should have a sound knowledge of experimental design and, where appropriate, statistical or analytical approaches to ensure the highest standards of methodological rigour.
