Management of global health trials: MRC guidelines

Guidelines for good clinical practice, trial oversight and management for Medical Research Council (MRC)-funded clinical trials in lower and middle income countries.

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MRC Clinical Trials Series. MRC Guidelines for Management of Global Health Trials Involving Clinical or Public Health Interventions (PDF)

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This guideline outlines principles for good clinical practice and trials management that apply to all trials of clinical and public health interventions in lower and middle income countries, including:

  • methods for diagnosis
  • treatment
  • disease prevention
  • management of service provision.

Clinical trials in the UK or EU are not covered in these guidelines.


  • 8 March 2022
    Guidance updated

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