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ESRC responsive mode: new investigator grants round two

This opportunity funds new researchers at the start of their careers to support them to become independent researchers through gaining experience of managing and leading research projects and teams.

You must be based at a UK research organisation eligible for ESRC funding.

ESRC responsive mode: research grants round two

This opportunity funds researcher-driven basic, applied, and strategic research from any disciplines and on any topics in ESRC’s remit, as long as the social sciences are more than 50% of the focus and effort.

You can be based at any eligible UK research organisation to apply for ESRC funding.

UKRI translation: MRC proof of concept: stage two

This funding opportunity was previously titled ‘Developmental pathway funding scheme: stage one’.

Apply for funding to develop and test novel therapeutics, medical devices, diagnostics and other interventions.

You must be employed at a research organisation eligible for MRC funding.

Expression of interest: First-of-a-Kind (FOAK) builder: programme entry

UK-registered businesses can apply for support worth up to £315,000 to develop a climate tech FOAK project.

Companies successful at this expression of interest stage could be invited to apply for a larger grant through FOAK builder phase two.

Large Grant full applications: November 2026 (invite only)

You can only apply for this funding opportunity if we have invited you to do so following a successful outline application.

Apply for funding to support innovative, large-scale and complex projects that tackle big science questions and have the potential to produce world-leading research.

Purchase mid-range equipment for biomedical research: MRC Equip

Funding opportunity for mid-range capital equipment that will enable and enhance research across MRC’s scientific areas.

You must be employed at a research organisation eligible to apply for MRC funding.

Invite only: Precision prevention: biological mechanisms of response variation

Apply for funding to study why people respond differently to biomedical prevention interventions. Projects must generate mechanistic evidence in humans to provide insight into precision prevention through better targeting.

You must be based at a UK research organisation eligible for MRC funding.

Economic Statistics Centre of Excellence 2027-2030 – invite only

This funding opportunity is designed to support the Economic Statistics Centre of Excellence’s (ESCoE) high-quality research to improve economic measurement, enhance the production of key statistics, and address challenges related to economic measurement over a three-year period.

Transformative sustainable AI technologies

Apply for funding for projects focused on speculative and high-risk research with the potential to deliver a step change in the sustainability of future AI systems.

You must be based at a UK research organisation eligible for UK Research and Innovation funding.

Frontier AI: SME Champions, phase 1

UK registered SME’s can apply for a share of up to £3.1 million to deliver feasibility studies for frontier artificial intelligence (AI), and machine learning (ML) technologies with a clear route to defensible scale-up.

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