This is the stage two (full applications) of the assessment process for strategic Longer and Larger (sLoLa) grants.
Applicants to stage two must have been invited from stage one (outline stage) of the funding opportunity process.
We are running this funding opportunity on the new UK Research and Innovation (UKRI) Funding Service so please ensure that your organisation is registered. You cannot apply on the Joint Electronic Submissions (Je-S) system.
The project lead is responsible for completing the application process on the Funding Service, but we expect all team members and project partners to contribute to the application.
Only the lead research organisation can submit an application to UKRI.
To apply
Select ‘Start application’ near the beginning of this Funding finder page.
- Confirm you are the project lead.
- Sign in or create a Funding Service account. To create an account, select your organisation, verify your email address, and set a password. If your organisation is not listed, email support@funding-service.ukri.org
Please allow at least 10 working days for your organisation to be added to the Funding Service. We strongly suggest that if you are asking UKRI to add your organisation to the Funding Service to enable you to apply to this opportunity, you also create an organisation Administration Account. This will be needed to allow the acceptance and management of any grant that might be offered to you.
- Answer questions directly in the text boxes. You can save your answers and come back to complete them or work offline and return to copy and paste your answers. If we need you to upload a document, follow the upload instructions in the Funding Service. All questions and assessment criteria are listed in the How to apply section on this Funding finder page.
- Allow enough time to check your application in ‘read-only’ view before sending to your research office.
- Send the completed application to your research office for checking. They will return it to you if it needs editing.
- Your research office will submit the completed and checked application to UKRI.
Where indicated, you can also demonstrate elements of your responses in visual form if relevant.
When including images, you must:
- provide a descriptive caption or legend for each image immediately underneath it in the text box (this must be outside the image and counts towards your word limit)
- insert each new image on a new line
- use files smaller than 5MB and in JPEG, JPG, JPE, JFI, JIF, JFIF, PNG, GIF, BMP or WEBP format
Images should only be used to convey important visual information that cannot easily be put into words. The following are not permitted, and your application will be rejected if you include:
- sentences or paragraphs of text
- tables
- excessive quantities of images
A few words are permitted where the image would lack clarity without the contextual words, such as a diagram, where text labels are required for an axis or graph column.
For more guidance on the Funding Service, see:
References
References should be included within the word count of the appropriate question section. You should use your discretion when including references and prioritise those most pertinent to the application.
Hyperlinks can be used in reference information. When including references, you should consider how your references will be viewed and used by the assessors, ensuring that:
- references are easily identifiable by the assessors
- references are formatted as appropriate to your research
- persistent identifiers are used where possible
General use of hyperlinks
Applications should be self-contained. You should only use hyperlinks to link directly to reference information. You must not include links to web resources to extend your application. Assessors are not required to access links to conduct assessment or recommend a funding decision.
Generative artificial intelligence (AI)
Use of generative AI tools to prepare funding applications is permitted, however, caution should be applied.
For more information see our policy on the use of generative AI in application and assessment.
Deadline
BBSRC must receive your application by 5 February 2026 at 4:00pm UK time.
You will not be able to apply after this time.
Make sure you are aware of and follow any internal institutional deadlines.
Following the submission of your application to the funding opportunity, your application cannot be changed, and applications will not be returned for amendment. If your application does not follow the guidance, it may be rejected.
BBSRC will provide outcomes and feedback for all full stage applications following the strategic Longer and Larger committee (SLC) panel.
Personal data
Processing personal data
BBSRC, as part of UKRI, will need to collect some personal information to manage your Funding Service account and the registration of your funding applications.
We will handle personal data in line with UK data protection legislation and manage it securely. For more information, including how to exercise your rights, read our privacy notice.
Sensitive information
If you or a core team member needs to tell us something you wish to remain confidential, email bbsrc.lolagrants@bbsrc.ukri.org
Include in the subject line: [the funding opportunity title; sensitive information; your Funding Service application number].
Typical examples of confidential information include:
- individual is unavailable until a certain date (for example due to parental leave)
- declaration of interest
- additional information about eligibility to apply that would not be appropriately shared in the ‘Applicant and team capability’ section
- conflict of interest for UKRI to consider in reviewer or panel participant selection
- the application is an invited resubmission
For information about how UKRI handles personal data, read UKRI’s privacy notice.
Institutional matched funding
There is no requirement for matched funding from the institutions hosting the project lead, project co-leads or other staff employed on the application, beyond the standard 20% FEC. Expert reviewers and panels assessing UKRI funding applications must not consider levels of institutional matched funding as a factor on which to base recommendations. Direct and in-kind contributions from third party project partners are encouraged.
This policy does not remove the need for support from host organisations who must provide the necessary research environment and infrastructure for award-specific activities funded by UKRI. For example, research facilities, training and development of staff.
Publication of outcomes
BBSRC, as part of UKRI, will publish the outcomes of this funding opportunity at Awarded research grants.
If your application is successful, we will publish some personal information on the UKRI Gateway to Research.
Summary
Word limit: 550
In plain English, provide a summary we can use to identify the most suitable experts to assess your application.
We usually make this summary publicly available on external-facing websites, therefore do not include any confidential or sensitive information. Make it suitable for a variety of readers, for example:
- opinion-formers
- policymakers
- the public
- the wider research community
Guidance for writing a summary
Clearly describe your proposed work in terms of:
- context
- the challenge the project addresses
- aims and objectives
- potential applications and benefits
Core team
List the key members of your team and assign them roles from the following:
- project lead (PL)
- project co-lead (UK) (PcL)
- researcher co-lead (RcL)
- specialist
- grant manager
- professional enabling staff
- research and innovation associate
- technician
Only list one individual as project lead.
UKRI has introduced a new addition to the ‘Specialist’ role type. Public contributors such as people with lived experience can now be added to an application.
Find out more about UKRI’s core team roles in funding applications.
Application questions
Successful outline application
Word limit: 5
Please provide the application reference number for your successful outline application.
Vision
Word limit: 2,000
What are you hoping to achieve with your proposed work?
What the assessors are looking for in your response
Explain how your proposed work:
- is of excellent quality and importance within or beyond the field(s) or area(s)
- has the potential to advance current understanding, or generate new knowledge, thinking or discovery within or beyond the field or area
- is timely given current trends, context, and needs
- is of sufficient novelty and ambition to warrant consideration for funding
- impacts world-leading research, society, the economy, or the environment
As part of this section, we expect you to:
- introduce the topic of research and explain its academic and wider context
- demonstrate a knowledge and understanding of past and current work in the subject area both in the UK and internationally
- provide a summary of the results and conclusions of your recent work in the research areas relevant to the proposal
- identify the overall aims of the proposed sLoLa research programme, set in the context the call’s frontier bioscience scope, current knowledge, and the leading edge within the research domains
Your project must be within the frontier bioscience scope of the funding opportunity.
References may be included within this section.
You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.
Approach
Word limit: 6,000
How are you going to deliver your proposed work?
What the assessors are looking for in your response
Explain how you have designed your approach so that it:
- is effective and appropriate to achieve your objectives
- is feasible, and comprehensively identifies any risks to delivery and how they will be managed
- uses a clearly written and transparent methodology (if applicable)
- summarises the previous work and describes how this will be built upon and progressed (if applicable)
- will maximise translation of outputs into outcomes and impacts
- describes how your, and if applicable your team’s, research environment (in terms of the place and relevance to the project) will contribute to the success of the work
As part of this section, we expect you to:
- provide the individual measurable objectives for the planned sLoLa and explain how these will be tackled. This should include a detailed description and justification for the methods and approaches to be employed
- describe the programme of work, indicating the research (experimental and data analysis) to be undertaken and the milestones that can be used to measure its progress. The detail should be sufficient to indicate the programme of work for each member of the research team
- highlight features which are particularly original or unique. sLoLa proposals are expected to be ambitious and potentially transformative, resulting in a step change in knowledge that will have a major impact on the research area
- identify any potential risks within the research programme and strategies to mitigate these risks, for example, alternative approaches
- identify any equipment or resources you will need to access
A project Gantt chart is compulsory and should be inserted as an image at the very end of this section. The Gantt chart should identify appropriate deliverables, responsibilities and time points for each objective.
References may be included within this section.
You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.
Strategic case
Word limit: 1,000
What is the strategic case for your sLoLa project?
What the assessors are looking for in your response
We expect you to:
- justify the need for sLoLa funding, describing the added value of funding through this mechanism and how the proposed work will demonstrate UK leadership in the field
- outline a clear strategy for how the research team’s outputs (experiments, data and results) will be fully integrated to deliver ‘greater than sum of parts’ outcomes
- describe the synergistic benefit of the team science approach to deliver project outcomes which could not be achieved through a series of smaller, shorter grants (for example, responsive mode awards) with individual groups working in isolation
- explain the significance and importance of the proposed research, including how the sLoLa award will enhance the international position of UK bioscience in the research area
- explain how the proposed research complements, and does not overlap with, other research funded in this area nationally and internationally including BBSRC’s research portfolio. For information on BBSRC’s portfolio, please see Gateway to Research and downloads on the funding opportunity webpage
- describe how the research programme will have an impact on the broader health and vitality of UK bioscience. Where applicable, this might include plans for ensuring the longer-term legacy of data, software, technologies or other community resources. This might also include skills and national capability developed during the project or identifying potential routes towards economic or societal impacts where these may already be evident
Research area
Word limit: 50
What phrases best describe the science area, or areas, covered in your proposed sLoLa project?
What the assessors are looking for in your response
Please provide three to five descriptions, such as plant science, cell biology, biophysics, developmental biology, microbiology or structural biology.
Methods used
Word limit: 50
What are the main methodologies in your proposed sLoLa project?
What the assessors are looking for in your response
This could include experimental methods (for example, microscopy or omics) and analytical approaches (for example, computational modelling or artificial intelligence).
Applicant and team capability to deliver
Word limit: 3,000
Why are you the right individual or team to successfully deliver the proposed work?
What the assessors are looking for in your response
Evidence of how you, and if relevant your team, have
- the relevant experience (appropriate to career stage) to deliver the proposed work
- the right balance of skills and expertise to cover the proposed work
- the appropriate leadership and management skills to deliver the work and your approach to develop others
- contributed to developing a positive research environment and wider community
You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.
The word limit for this section is 3,000 words: 2,500 words to be used for R4RI modules (including references) and, if necessary, a further 500 words for Additions.
Use the Résumé for Research and Innovation (R4RI) format to showcase the range of relevant skills you and, if relevant, your team (project and project co-leads, researchers, technicians, specialists, partners and so on) have and how this will help deliver the proposed work. You can include individuals’ specific achievements but only choose past contributions that best evidence their ability to deliver this work.
Complete this section using the R4RI module headings listed. Use each heading once and include a response for the whole team, see the UKRI guidance on R4RI. You should consider how to balance your answer, and emphasise where appropriate the key skills each team member brings:
- contributions to the generation of new ideas, tools, methodologies, or knowledge
- the development of others and maintenance of effective working relationships
- contributions to the wider research and innovation community
- contributions to broader research or innovation users and audiences and towards wider societal benefit
We expect applications to describe the specific contribution of each applicant to the proposed sLoLa such as: their scientific contributions, for example, research field and specialist knowledge, experience, technical and data analysis expertise
- their role and responsibilities, for example, managerial, leadership, mentoring
- references to specific work packages are recommended
- highlight where applicants will work collaboratively to deliver specific project requirements
- include clear time commitments for each applicant
We expect applicants to describe how each applicant has contributed to the generation of new ideas, knowledge, tools, or methodologies. Examples might include:
- contributions to (and skills acquired from) past research projects
- key outputs such as publications, datasets, software and intellectual property
The most relevant examples are likely to relate to previous work related to the proposed sLoLa project.
We expect applicants to describe how team members have contributed to the effective working of research teams. Examples might include:
- contributions to (and skills acquired from) past project management, supervision, mentoring or line management activities which were critical to the success of a team
- strategic leadership which shaped the direction of a team or organisation, personal development activities, management of complex multi-investigator or multi-site projects
Examples provided should evidence the team’s collective capability to lead and manage the proposed sLoLa project.
We expect applicants to describe how teams will support the development of staff employed by this proposal such as early career researchers and technicians. Examples might include training, development of leadership or management, scientific writing skills.
We expect applicants to describe how team members have contributed to the wider research and innovation community. Examples might include contributions to wider collaborations and networks, establishment of community resources, contributions to the improvement of research culture including equality, diversity and inclusion practices and commitments such as editing, reviewing and committees.
We expect applicants to describe how team members have contributed to broader society. Examples might include engagement across the public, private sector, with the wider public, or past research which has influenced policy development.
Additions
Provide any further details relevant to your application. This section is optional and can be up to 500 words. You should not use it to describe additional skills, experiences, or outputs, but you can use it to describe any factors that provide context for the rest of your R4RI (for example, details of career breaks if you wish to disclose them).
In this section you can reference anticipated contributions of any collaborators, project partners or sub-contractors.
A project partner is a collaborating organisation who will have an integral role in the proposed research. This may include direct (cash) or indirect (in-kind) contributions such as expertise, staff time or use of facilities. Project partners may be in industry, academia, third sector or government organisations in the UK or overseas, including partners based in the EU.
Complete this as a narrative. Do not format it like a CV.
References may be included within this section.
The roles in funding applications policy has descriptions of the different project roles.
Management strategy
Word limit: 700 words
How do you plan to manage the sLoLa?
What the assessors are looking for in your response
We expect you to:
- describe how the project will be managed to ensure effective working of the team, effective utilisation of resources, and successful delivery of the planned outcomes. The management approach should be appropriate to the nature and scale of the programme
- describe how the project will have governance arrangements appropriate for the oversight and successful delivery of the project’s complexity
- provide details about the project’s management and advisory structure
- provide details of the approach to project and risk management, and the monitoring strategy for tracking progress of the proposed programme
- provide information on the proposed membership of the scientific advisory board and how it will be used. A scientific advisory board is required for all projects, which is independent from both the academic institutions and project partners involved in the proposal
You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.
Scientific advisory board (SAB) members
Word limit: 50
Please provide the name and institution of the proposed SAB members for your project. This information will be used to prevent conflicts in the assessment of your application.
Please see ‘Strategic Advisory Board Guidance’ in Additional information’ under ‘Supporting documents for further information.
Ethics and responsible research and innovation (RRI)
Word limit: 500
What are the ethical or RRI implications and issues relating to the proposed work? If you do not think that the proposed work raises any ethical or RRI issues, explain why.
What the assessors are looking for in your response
Demonstrate that you have identified and evaluated:
- the relevant ethical or responsible research and innovation considerations
- how you will manage these considerations
You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.
Genetic and biological risk
Word limit: 700
Does your proposed research involve any genetic or biological risk?
What the assessors are looking for in your response
In respect of animals, plants or microbes, are you proposing to:
- use genetic modification as an experimental tool, like studying gene function in a genetically modified organism
- release genetically modified organisms
- ultimately develop commercial and industrial genetically modified outcomes
If yes, provide the name of any required approving body and state if approval is already in place. If it is not, provide an indicative timeframe for obtaining the required approval.
Identify the organism or organisms as a plant, animal or microbe and specify the species and which of the three categories the research relates to.
Identify the genetic and biological risks resulting from the proposed research, their implications, and any mitigation you plan on taking. Assessors will want to know you have considered the risks and their implications to justify that any identified risks do not outweigh any benefits of the proposed research.
If this does not apply to your proposed work, you will be able to indicate this in the Funding Service.
Research involving the use of animals
Does your proposed research involve the use of vertebrate animals or other organisms covered by the Animals Scientific Procedures Act?
What the assessors are looking for in your response
If you are proposing research that requires using animals, download and complete the Research involving the use of animals template (DOCX, 52.5KB), which contains all the questions relating to research using vertebrate animals or other Animals (Scientific Procedures) Act 1986 regulated organisms.
Save it as a PDF. The Funding Service will provide document upload details when you apply.
If this does not apply to your proposed work, you will be able to indicate this in the Funding Service.
Conducting research with animals overseas
Word limit: 700
Will any of the proposed animal research be conducted overseas?
What the assessors are looking for in your response
If you are proposing to conduct overseas research, it must be conducted in accordance with welfare standards consistent with those in the UK, as in Responsibility in the use of animals in bioscience research. Ensure all named applicants in the UK and overseas are aware of this requirement.
If your application proposes animal research to be conducted overseas, you must provide a statement in the text box. Depending on the species involved, you may also need to upload a completed template for each species listed.
Statement
Provide a statement to confirm that:
- all named applicants are aware of the requirements and have agreed to abide by them
- this overseas research will be conducted in accordance with welfare standards consistent with the principles of UK legislation
- the expectation set out in Responsibility in the use of animals in bioscience research will be applied and maintained
- appropriate national and institutional approvals are in place
Templates
Overseas studies proposing to use non-human primates, cats, dogs, equines or pigs will be assessed during NC3Rs review of research applications. Provide the required information by completing the template from the question ‘Research involving the use of animals’.
For studies involving other species, such as:
- rodents
- rabbits
- sheep
- goats
- pigs
- cattle
- xenopus laevis and xenopus tropicalis
- zebrafish
Select, download, and complete the relevant Word checklist or checklists by exploring NC3Rs checklist for the use of animals overseas.
Save your completed template as a PDF and upload to the Funding Service. If you use more than one checklist template, save it as a single PDF.
The Funding Service will provide document upload details when you apply.
If conducting research with animals overseas does not apply to your proposed work, you will be able to indicate this in the Funding Service.
Research involving human participation
Word limit: 700
Will the project involve the use of human subjects or their personal information?
What the assessors are looking for in your response
If you are proposing research that requires the involvement of human subjects, provide the name of any required approving body and whether approval is already in place.
Justify the number and the diversity of the participants involved, as well as any procedures.
Provide details of any areas of substantial or moderate severity of impact.
If this does not apply to your proposed work, you will be able to indicate this in the Funding Service.
Research involving human tissues or biological samples
Word limit: 700
Does your proposed research involve the use of human tissues, or biological samples?
What the assessors are looking for in your response
If you are proposing work that involves human tissues or biological samples, provide the name of any required approving body and whether approval is already in place.
Justify the use of human tissue or biological samples specifying the nature and quantity of the material to be used and its source.
If this does not apply to your proposed work, you will be able to indicate this in the Funding Service.
Resources and cost justification
Word limit: 3,000
What will you need to deliver your proposed work and how much will it cost?
What the assessors are looking for in your response
Justify the application’s more costly resources, in particular:
- project staff
- significant travel for field work or collaboration (but not regular travel between collaborating organisations or to conferences)
- any equipment that will cost more than £25,000
- any consumables beyond typical requirements, or that are required in exceptional quantities
- all facilities and infrastructure costs
- all resources that have been costed as ‘Exceptions’
Please be aware that BBSRC will fund 80% of the full economic cost (FEC).
You can request costs associated with reasonable adjustments where they increase as a direct result of working on the project. For further information see Disability and accessibility support for UKRI applicants and grant holders.
Assessors are not looking for detailed costs or a line-by-line breakdown of all project resources. Overall, they want you to demonstrate how the resources you anticipate needing for your proposed work:
- are comprehensive, appropriate, and justified
- represent the optimal use of resources to achieve the intended outcomes
- maximise potential outcomes and impacts
Your organisation’s support
Word limit: 10
Provide details of support from your research organisation.
What the assessors are looking for in your response
Provide a statement of support from your research organisation detailing how they will support you, as the applicant, and your proposed activities. This should include details of any matched funding that will be provided to support the activity and any additional support that might add value to the work.
Assessors will be looking for a strong statement of support from your research organisation. This information should have been approved for submission by an appropriate institutional authority.
You must also include the following details:
- a significant person’s name, their position and office or department, or all
- office address or web link
Upload details are provided within the Funding Service on the actual application.
Project partners
Add details about any project partners’ contributions. If there are no project partners, you can indicate this on the Funding Service.
A project partner is a collaborating organisation who will have an integral role in the proposed research. This may include direct contributions for example cash, donated equipment and resources, or staff seconded to the project, or indirect and in-kind contributions for example use of project partner’s equipment, datasets, or facilities. Project partners may be in industry, academia, third sector or government organisations in the UK or overseas, including partners based in the EU.
Add the following project partner details:
- the organisation name and address (searchable via a drop-down list or enter the organisation’s details manually, as applicable)
- the project partner contact name and email address
- the type of contribution (direct or indirect) and its monetary value
If a detail is entered incorrectly and you have saved the entry, remove the specific project partner record and re-add it with the correct information.
For audit purposes, UKRI requires formal collaboration agreements to be put in place if an award is made.
Project partners: letters (or emails) of support
Upload a single PDF containing the letters or emails of support from each partner you named in the Project partners section. These should be uploaded in English or Welsh only.
What the assessors are looking for in your response
Enter the words ‘attachment supplied’ in the text box, or if you do not have any project partners enter ‘N/A’. Each letter or email you provide should:
- confirm the partner’s commitment to the project
- clearly explain the value, relevance, and possible benefits of the work to them
- describe any additional value that they bring to the project
- have a page limit of two sides A4 per partner
The Funding Service will provide document upload details when you apply.
If you do not have any project partners, you will be able to indicate this in the Funding Service.
Ensure you have prior agreement from project partners so that, if you are offered funding, they will support your project as indicated in the project partners’ section.
For audit purposes, UKRI requires formal collaboration agreements to be put in place if an award is made.
Data management and sharing
Word limit: 1,000
How will you manage and share data collected or acquired through the proposed research?
What the assessors are looking for in your response
Provide a data management plan that clearly details how you will comply with UKRI’s published data sharing policy, which includes detailed guidance notes.
Facilities
Word limit: 600
Does your proposed research require the support and use of a facility?
What the assessors are looking for in your response
If you will need to use a facility, follow your proposed facility’s normal access request procedures. Ensure you have prior agreement so that if you are offered funding, they will support the use of their facility on your project.
For each requested facility you will need to provide the:
- name of facility, copied and pasted from the facility information list (DOCX, 42KB)
- proposed usage or costs, or costs per unit where indicated on the facility information list
- confirmation you have their agreement where required
Facilities should only be named if they are on the facility information list above. If you will not need to use a facility, you will be able to indicate this in the Funding Service.
Trusted Research and Innovation (TR&I)
Word limit: 100
Does your proposed work relate to UKRI’s Trusted Research and Innovation principles?
What the assessors are looking for in your response
Demonstrate how your proposed work relates to UKRI’s Trusted Research and Innovation principles including:
- list any dual-use (both military and non-military) applications to your research
- if this project is relevant to one or more of the 17 areas of the UK National Security and Investment (NSI) Act, please list the area(s)
- please read the academic export control guidance and confirm if an export control licence is required for this project and the status of any application(s)
- if your project involves any items or substances on the UK strategic export control list, please provide a list
We may ask you to provide additional TR&I information later, in line with UKRI TR&I principles and funding terms and conditions (RGC 2.6.2, 2.7.1 and 2.7.2).
International collaboration
Word limit: 100
Does the proposed work involve any international collaboration or engagement?
What the assessors are looking for in your response
Provide details about your expected international collaboration or engagement, including:
- a list of the countries your international project co-leads, project partners, visiting researchers, or other collaborators are based in
- details of any subcontractors or service providers
If your proposed work does not involve international collaboration or engagement, you will be able to indicate this in the Funding Service.
Individuals based at an international organisation are not eligible to be a member of the core team as they are not eligible for BBSRC funding for this opportunity.
