Funding opportunity

Funding opportunity: 2026 to 2027 strategic Longer and Larger (sLoLa): full stage

Apply for funding to undertake a large team-based curiosity-driven bioscience discovery research project.

Your project should demonstrate:

  • the potential for major breakthroughs in our fundamental understanding of living systems
  • a fully integrated team science approach
  • the need for longer and larger scale funding
  • enhancing the capability and capacity of UK biosciences

The full economic cost of your project must be over £2 million. BBSRC will fund 80% of the full economic cost.

Projects can be up to five years in duration.

Full stage submissions are invitation only following assessment of an sLoLa outline application.

Who can apply

You can only apply for this funding opportunity if we have invited you to do so following a successful outline application of the 2026 to 2027 sLoLa application process.

This funding opportunity is open to organisations with standard eligibility. Check if your organisation is eligible.

Who is eligible to apply

This funding opportunity is open to teams of eligible researchers at:

  • higher education institutions
  • research council institutes
  • approved independent research organisations
  • public sector research establishments

A single project lead, who will be the main contact for Biotechnology and Biological Sciences Research Council (BBSRC), must be designated for administrative purposes.

Project lead and co-lead eligibility

There is no requirement for project leads nor project co-leads to have held a similar sized award before. We regard this programme as an important means for developing research careers and we welcome applications which involve early and mid-career researchers eligible for BBSRC funding as project lead or project co-lead.

We expect the leadership of the project for this funding opportunity to be adequately and responsibly resourced. The intellectual leadership and overall management of the project (including work packages or staff) may be shared with any number of project co-leads at any number of eligible research organisations as part of a team science endeavour, with roles clearly specified in the application.

UKRI supports over 25,000 FTE research and innovation (R&I) staff directly on grants, many more if indirect costs, facility charges and strategic funding streams are included. Those skilled people and teams design our studies, deliver the R&I work and disseminate the outputs. They are the R&I system and critical to delivering the outcomes we invest in.

Our expectations for people and teams are collated on the supporting skills and talent section of the good research resource hub. In this opportunity, we are piloting a new approach to embedding consideration of people and teams in our assessment. Some of the assessment criteria have been updated to reflect this. See the background to the pilot.

Project or grant managers

We encourage the inclusion of a project or grant manager in the core team of all sLoLa applications. This is to provide support to the leadership team in day-to-day project coordination, tracking of progress, governance and resource management. Please see ‘Project or grant manager guidance’ in ‘Additional information’ under supporting documents for further information.

Research technical professionals

Building on the Technician Commitment UKRI Action Plan and the UKRI people and teams action plan, we encourage the inclusion of research technical professionals in the ‘Core team’ section including as project co-leads or researcher co-leads where appropriate.

Project partners

A project partner is a collaborating organisation who will have an integral role in the proposed research. This may include direct (cash) or indirect (in-kind) contributions such as expertise, staff time or use of facilities.

Project partners may be in industry, academia, third sector or government organisations in the UK or overseas, including partners based in the EU. Please see Roles in funding applications: eligibility, responsibilities and costings guidance for more information.

Who is not eligible to apply

Multiple applications with the same project lead are not permitted within the same funding round.

Project leads of currently active sLoLa awards may not apply as a project leads in this funding round, unless their grant is in its final year.

Individuals based at an international organisation are not eligible to be a member of the core team as they are not eligible for BBSRC funding for this opportunity. International collaborators can be added as project partners on an application, please see Roles in funding applications: eligibility, responsibilities and costings guidance for more information.

Resubmissions

We will not accept uninvited resubmissions of projects that have been submitted to UKRI. Find out more about UKRI’s resubmission policy.

Equality, diversity and inclusion

We are committed to achieving equality of opportunity for all funding applicants. We encourage applications from a diverse range of researchers.

We support people to work in a way that suits their personal circumstances. This includes:

  • career breaks
  • support for people with caring responsibilities
  • flexible working
  • alternative working patterns

UKRI can offer disability and accessibility support for UKRI applicants and grant holders during the application and assessment process.

What we're looking for

Demand management

Demand management is not being applied to this funding opportunity.

Scope

Bioscience discovery research

Projects must be focused on delivering conceptual advances and fundamental understanding of biological systems.

Projects are expected to generate new fundamental biological knowledge of broad and long-term significance, changing how we think about bioscience within and likely transcending their immediate fields. They should have the potential to make transformational, not incremental, contributions to our understanding of the principles which govern biological processes and systems, thereby contributing to our understanding of important ‘rules of life’.

Projects must be primarily within BBSRC remit and can investigate ideas within or across any scale of biological organisation from molecules to organisms and populations. We particularly encourage applications which take multimodal and multiscale approaches, integrating data-driven and experimental approaches from different bioscience disciplines.

Projects will typically use cutting-edge technologies, methods and approaches to explore the frontiers of the topic under investigation. We encourage applications that incorporate development of state-of-the-art technology that will unlock new opportunities to revolutionise the discovery of novel biological knowledge.

Applications that are not principally designed to deliver new fundamental bioscience knowledge are unsuitable and likely to be excluded. Examples of unsuitable applications include those where the primary aim is to apply knowledge to tackle contemporary socio-economic challenges related to end-user driven objectives from within industry or sustainable development goals.

Longer and larger scale

Through an original and fully integrated research project, your idea must have the potential to lead to a major new contribution to biological knowledge, commensurate with the longer and larger scale of support provided.

Your application must provide a clear justification for the necessity of the longer and larger scale of funding through the sLoLa scheme, to the extent that the work could not be undertaken through several separate smaller awards, either in parallel or in series.

Your application must include a clear strategy for the integration of data and results generated such that the overall outcomes of the project are substantively different than the outcomes of individual work packages.

Your application must demonstrate overall coherence, connectivity, coordination and integration of the work to be carried out. This includes how the team will deliver substantively different and synergistic outcomes than could be achieved through the efforts of individual members or their research groups working in isolation.

Applications that lack a clear case for the need of longer and larger scale funding will be at a competitive disadvantage and may be excluded.

Team science

Your application is expected to assemble a diverse and distinctive team of researchers and other specialists drawn from the full breadth of expertise available across the UK with the collective capability of delivering the proposed work. Typically, this will span several research organisations or departments, or both.

Consideration of equality, diversity and inclusion is important for all applications to BBSRC for funding, and we expect particular care to be taken for larger projects involving multiple co-applicants such as those supported through the sLoLa scheme. You are expected to evaluate and consider these issues from the earliest stage of building your teams through to the delivery and outcomes of awarded projects.

Teams must collectively demonstrate a comprehensive range of scientific, technical, leadership, and management expertise to effectively deliver the proposed work’s scale and complexity. Consideration should be given to how a larger-scale team that may be distributed across multiple sites will communicate and effectively coordinate their work. Applications are encouraged to include dedicated project management support.

We encourage applicants to adopt distributed leadership and management models to share opportunities and responsibilities across the sLoLa team. Each team member’s unique roles and responsibilities should be clearly outlined and justified.

There is no requirement for project leads nor project co-leads to have held a similar sized award before. However, it should be clear how any individual holding significant scientific, leadership or management responsibilities will be mentored, or otherwise supported by the wider team or institutional environment, including through appropriate development opportunities.

This is particularly important where an individual is stepping into a position with a greater degree of leadership or management responsibility than they have previously held.

We encourage you to embed equality, diversity and inclusion considerations throughout your activities, including outreach activities that engage individuals across different career paths, career stages, expertise levels, and underrepresented groups, where relevant.

We encourage you to consider how your project and resourcing approach will support staff development and provide enhanced opportunities for all team members including:

  • strengthening long term specialist and technical capacity
  • promoting skills development, collaboration and cross-disciplinary working across research groups and institutions
  • build high quality leadership and management capability, including inclusive governance

Teams are encouraged to include researchers from the full depth and breadth of the UK’s diverse research and innovation talent pool, including different career pathways and stages. You should follow the principles of the Concordat to Support the Career Development of Researchers and the Technician Commitment.

Most sLoLa projects are expected to generate significant amounts of data, and therefore the key themes outlined in our recent Review of Data Intensive Biosciences should be carefully considered when assembling a research team.

Strategic position

The proposed work should establish or significantly enhance an exceptional and unique bioscience research capability in the UK. Projects should lead to significant and distinctive improvements to health and vitality of UK bioscience in the area under investigation, raising its international profile to the point of being recognised as world-leading.

Your application should include consideration of how the proposed research fits with and complements other active UK and international research in the area, or areas, under investigation.

We encourage teams to think about public engagement activities from the start of the project and how team members can contribute to this. Within the sLoLa scheme, you may include well designed and strategically aligned public engagement activities that clearly relate to the proposed research area. You can request the associated costs for these activities, provided they are fully justified and integrated into the overall work plan.

To facilitate the positioning of your application against the wider landscape of research investments, see the list of currently active BBSRC grants over £2 million in the supporting document section of this funding opportunity. This is not an exhaustive account, and you should consult other resources to build and demonstrate your own knowledge of the wider landscape.

We take a strategic approach to investments, considering the overall balance of our portfolio in bioscience research. Applications in areas in which there is already substantial BBSRC, or other UK Research and Innovation (UKRI) research council investment, will be at a competitive disadvantage if significantly overlapping these investments and may be excluded.

Particular attention should be paid to existing sLoLa-scale awards or research in areas covered by our institute strategic programme grants.

Remit

Work principally outside of our remit will be excluded. We encourage multidisciplinary applications, but we strongly advise potential applicants to contact us at bbsrc.lolagrants@bbsrc.ukri.org before submission if you suspect substantial aspects of the application may be outside of our remit.

Duration

The duration of this award is up to five years.

It is anticipated that awarded grants will start in the latter half of the 2027 to 2028 financial year.

Funding available

The full economic cost of your project must be at least £2 million.

Biotechnology and Biological Sciences Research Council (BBSRC) will fund 80% of the full economic cost (FEC).

The indicative budget agreed for this year’s funding opportunity is set at a baseline of and we anticipate being able to fund two to three projects, subject to the quality of applications received and the available budget.

Supporting skills and talent

We encourage you to follow the principles of the Concordat to Support the Career Development of Researchers and the Technician Commitment.

Trusted Research and Innovation (TR&I)

UK Research and Innovation (UKRI) has a long-standing and continuing commitment to supporting and enabling safe and effective collaboration in research and innovation. UKRI is equally committed to ensuring that this takes place with integrity and within strong ethical frameworks.

Our Principles and expectations set out the principles that UKRI applies to TR&I and our general expectations of the research organisations (including businesses, research institutes, and research technical organisations) that we support. Organisations supported by UKRI should be able to provide evidence that their internal controls and processes meet these expectations.

See further guidance and information about TR&I, including where applicants can find additional support.

How to apply

This is the full stage (stage two) of the assessment process for strategic Longer and Larger (sLoLa) grants.

Applicants to stage two must have been invited from outlines (stage one) of the funding opportunity process.

We are running this funding opportunity on the new UK Research and Innovation (UKRI) Funding Service so please ensure that your organisation is registered. You cannot apply on the Joint Electronic Submissions (Je-S) system.

The project lead is responsible for completing the application process on the Funding Service, but we expect all team members and project partners to contribute to the application.

Only the lead research organisation can submit an application to UKRI.

To apply

Select ‘Start application’ near the beginning of this Funding finder page.

  1. Confirm you are the project lead.
  2. Sign in or create a Funding Service account. To create an account, select your organisation, verify your email address, and set a password.
  3. Answer questions directly in the text boxes. You can save your answers and come back to complete them or work offline and return to copy and paste your answers. If we need you to upload a document, follow the upload instructions in the Funding Service. All questions and assessment criteria are listed in the How to apply section on this Funding finder page.
  4. Allow enough time to check your application in ‘read-only’ view before sending to your research office.
  5. Send the completed application to your research office for checking. They will return it to you if it needs editing.
  6. Your research office will submit the completed and checked application to UKRI.

Please be aware that research office and finance teams undertake checks on hosting arrangements and financial eligibility. The ultimate responsibility for ensuring compliance with all opportunity requirements lies with the applicant.

Where indicated, you can also demonstrate elements of your responses in visual form if relevant.

When including images, you must:

  • provide a descriptive caption or legend for each image immediately underneath it in the text box (this must be outside the image and counts towards your word limit)
  • insert each new image on a new line
  • use files smaller than 5MB and in JPEG, JPG, JPE, JFI, JIF, JFIF, PNG, GIF, BMP or WEBP format

Images should only be used to convey important visual information that cannot easily be put into words. The following are not permitted, and your application will be rejected if you include:

  • sentences or paragraphs of text
  • tables
  • excessive quantities of images

A few words are permitted where the image would lack clarity without the contextual words, such as a diagram, where text labels are required for an axis or graph column.

For more guidance on the Funding Service, see:

References

References should be included within the word count of the appropriate question section. You should use your discretion when including references and prioritise those most pertinent to the application.

Hyperlinks can be used in reference information. When including references, you should consider how your references will be viewed and used by the assessors, ensuring that:

  • references are easily identifiable by the assessors
  • references are formatted as appropriate to your research
  • persistent identifiers are used where possible

General use of hyperlinks

Applications should be self-contained. You should only use hyperlinks to link directly to reference information. You must not include links to web resources to extend your application. Assessors are not required to access links to conduct assessment or recommend a funding decision.

Generative artificial intelligence (AI)

Use of generative AI tools to prepare funding applications is permitted, however, caution should be applied.

For more information see our policy on the use of generative AI in application and assessment.

Deadline

Biotechnology and Biological Sciences Research Council (BBSRC) must receive your application by 9 February 2027 at 4:00pm UK time.

Only applicants who are invited by BBSRC will be able to submit a stage two full application to this funding opportunity.

You will not be able to apply after this time.

Make sure you are aware of and follow any internal institutional deadlines.

Following the submission of your application to this funding opportunity, your application cannot be changed, and submitted applications will not be amended. If your application does not follow the guidance, it may be rejected.

BBSRC will provide outcomes and feedback for all full stage applications following the strategic Longer and Larger committee (SLC) panel.

Personal data

Processing personal data

BBSRC, as part of UKRI, will need to collect some personal information to manage your Funding Service account and the registration of your funding applications.

We will handle personal data in line with UK data protection legislation and manage it securely. For more information, including how to exercise your rights, read our privacy notice.

Sensitive information

If you or a core team member need to tell us something you wish to remain confidential, email bbsrc.lolagrants@bbsrc.ukri.org

Include in the subject line: [the funding opportunity title; sensitive information; your Funding Service application number].

Typical examples of confidential information include:

  • individual is unavailable until a certain date (for example due to parental leave)
  • declaration of interest
  • additional information about eligibility to apply that would not be appropriately shared in the ‘Applicant and team capability’ section
  • conflict of interest for UKRI to consider in reviewer or panel participant selection
  • the application is an invited resubmission

For information about how UKRI handles personal data, read UKRI’s privacy notice.

Institutional matched funding

There is no requirement for matched funding from the institutions hosting the project lead, project co-leads or other staff employed on the application, beyond the standard 20% FEC. Expert reviewers and panels assessing UKRI funding applications must not consider levels of institutional matched funding as a factor on which to base recommendations. Direct and in-kind contributions from third party project partners are encouraged.

This policy does not remove the need for support from host organisations who must provide the necessary research environment and infrastructure for award-specific activities funded by UKRI. For example, research facilities, training and development of staff.

People and teams assessment pilot

This funding opportunity is part of the people and teams assessment pilot. The pilot will embed consideration of people and teams in application and assessment. The assessment criteria considered in the pilot are:

  • approach
  • applicant and team capability to deliver
  • resources and cost justification

Publication of outcomes

BBSRC, as part of UKRI, will publish the outcomes of this funding opportunity at Awarded research grants.

If your application is successful, we will publish some personal information on the UKRI Gateway to Research.

Summary

Word limit: 550

In plain English, provide a summary we can use to identify the most suitable experts to assess your application.

We usually make this summary publicly available on external-facing websites, therefore do not include any confidential or sensitive information. Make it suitable for a variety of readers, for example:

  • opinion-formers
  • policymakers
  • the public
  • the wider research community

Guidance for writing a summary

Clearly describe your proposed work in terms of:

  • context
  • the challenge the project addresses
  • aims and objectives
  • potential applications and benefits

Core team

List the key members of your team and assign them roles from the following:

  • project lead (PL)
  • project co-lead (UK) (PcL)
  • researcher co-lead (RcL)
  • specialist
  • grant manager
  • professional enabling staff
  • research and innovation associate
  • technician

Only list one individual as project lead.

UKRI has introduced a new addition to the ‘Specialist’ role type. Public contributors such as people with lived experience can now be added to an application.

Find out more about UKRI’s core team roles in funding applications.

Questions we will ask you

Application questions

Vision

Word limit: 2,000

What are you hoping to achieve with your proposed work?

What the assessors are looking for in your response

Explain how your proposed work:

  • is of excellent quality and importance within or beyond the field(s) or area(s)
  • has the potential to advance current understanding, or generate new knowledge, thinking or discovery within or beyond the field or area
  • is timely given current trends, context, and needs
  • impacts world-leading research, society, the economy, or the environment
  • is of sufficient novelty and ambition to warrant consideration for funding

Within the vision we also expect you to:

  • introduce the topic of research and explain its academic and wider context
  • demonstrate a knowledge and understanding of past and current work in the subject area both in the UK and internationally
  • provide a summary of the results and conclusions of your recent work in the research areas relevant to the proposal
  • identify the overall aims of the proposed sLoLa research programme, set in the context the funding opportunity’s frontier bioscience scope, current knowledge, and the leading edge within the research domains

Your project must be within the bioscience discovery research scope of the funding opportunity.

References may be included within this section.

You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.

Approach

Word limit: 6,000

How are you going to deliver your proposed work?

What the assessors are looking for in your response

Explain how you have designed your approach so that it:

  • is effective and appropriate to achieve your objectives
  • is feasible, and comprehensively identifies any risks to delivery and how they will be managed
  • uses a clearly written and transparent methodology (if applicable)
  • summarises the previous work and describes how this will be built upon and progressed (if applicable)
  • will maximise translation of outputs into outcomes and impacts
  • describes how your, and if applicable your team’s, research environment (in terms of the place and relevance to the project) will contribute to the success of the work

As part of this section, we expect you to:

  • provide the individual measurable objectives for the planned sLoLa and explain how these will be tackled. This should include a detailed description and justification for the methods and approaches to be employed
  • describe the programme of work, indicating the research (experimental and data analysis) to be undertaken and the milestones that can be used to measure its progress. The detail should be sufficient to indicate the programme of work for each member of the research team
  • highlight features which are particularly original or unique. sLoLa proposals are expected to be ambitious and potentially transformative, resulting in a step change in knowledge that will have a major impact on the research area
  • identify any potential risks within the research programme and strategies to mitigate these risks, for example, alternative approaches
  • identify any equipment or resources you will need to access

A project Gantt chart is compulsory and should be inserted as an image at the very end of this section. The Gantt chart should identify appropriate deliverables, responsibilities and time points for each objective.

References may be included within this section.

You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.

Applicant and team capability to deliver

Word limit: 3,000

Why are you the right individual or team to successfully deliver the proposed work?

What the assessors are looking for in your response

Evidence of how you, and if relevant your team, have:

  • the relevant experience (appropriate to career stage) to deliver the proposed work
  • the right balance of skills and expertise to cover the proposed work
  • the appropriate leadership and management skills to deliver the work and your approach to develop others (including how technical, specialist, professional and leadership capabilities are integrated and supported within the team)
  • used technical and specialist capabilities within your organisation(s) in building your project team
  • collaborated with technical and specialist team members to enhance building technical and specialist capabilities within your project
  • contributed to developing a positive research environment and wider community
  • contributed to the generation of new ideas, tools, methodologies, or knowledge. sLoLa awards are expected to use a variety of experimental techniques and generate a large amount of data so care should be taken to highlight both experimental and analytical experience directly relevant to the proposed research
  • contributed to the inclusion and development of others
  • contributed to the maintenance of effective working relationships
  • contributed to the wider research and innovation community
  • contributed to broader research or innovation users and audiences and towards wider societal benefit

The core leadership team should consist of the project lead and the project co-leads identified on the outline application.

Showcase the range of relevant skills you and, if relevant, your team (project and project co-leads, researchers, technicians, specialists, partners and so on) have and how this will help deliver the proposed work.

You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.

The word limit for this section is 3,000 words: 2,500 words to be used for Résumé for Research and Innovation (R4RI) modules (including references) and, if necessary, a further 500 words for Additions.

Use the R4RI format to showcase the range of relevant skills you and, if relevant, your team (project and project co-leads, researchers, technicians, specialists, partners and so on) have and how this will help deliver the proposed work. You can include individuals’ specific achievements but only choose past contributions that best evidence their ability to deliver this work.

Complete this section using the R4RI module headings listed. Use each heading once and include a response for the whole team, see the UKRI guidance on R4RI. You should consider how to balance your answer, and emphasise where appropriate the key skills each team member brings:

  • contributions to the generation of new ideas, tools, methodologies, or knowledge
  • the development of others and maintenance of effective working relationships
  • contributions to the wider research and innovation community
  • contributions to broader research or innovation users and audiences and towards wider societal benefit

We expect applications to describe the specific contribution of each applicant to the proposed sLoLa such as: their scientific contributions, for example, research field and specialist knowledge, experience, technical and data analysis expertise

  • their role and responsibilities, for example, managerial, leadership, mentoring
  • references to specific work packages are recommended
  • highlight where applicants will work collaboratively to deliver specific project requirements
  • include clear time commitments for each applicant
Additions

Provide any further details relevant to your application. This section is optional and can be up to 500 words. You should not use it to describe additional skills, experiences, or outputs, but you can use it to describe any factors that provide context for the rest of your R4RI (for example, details of career breaks if you wish to disclose them).

In this section you can reference anticipated contributions of any collaborators, project partners or sub-contractors.

A project partner is a collaborating organisation who will have an integral role in the proposed research. This may include direct (cash) or indirect (in-kind) contributions such as expertise, staff time or use of facilities. Project partners may be in industry, academia, third sector or government organisations in the UK or overseas, including partners based in the EU.

Complete this as a narrative. Do not format it like a CV.

References may be included within this section.

Resources and cost justification

Word limit: 3,000

What will you need to deliver your proposed work and how much will it cost?

What the assessors are looking for in your response

Justify the application’s more costly resources, in particular:

  • project staff
  • significant travel for field work or collaboration (but not regular travel between collaborating organisations or to conferences), this can include travel costs for SAB members
  • any equipment that will cost more than £25,000
  • any consumables beyond typical requirements, or that are required in exceptional quantities
  • all facilities and infrastructure costs
  • all resources that have been costed as ‘Exceptions’

You can request costs associated with reasonable adjustments where they increase as a direct result of working on the project. For further information see Disability and accessibility support for UKRI applicants and grant holders. Where a funding limit is imposed on the opportunity, requested costs for reasonable adjustments may exceed the maximum funding amount.

Assessors are not looking for detailed costs or a line-by-line breakdown of all project resources. Overall, they want you to demonstrate how the resources you anticipate needing for your proposed work:

  • are comprehensive, appropriate, and justified
  • represent the optimal use of resources to achieve the intended outcomes
  • maximise potential outcomes and impacts
Team communication platforms

We encourage applicants to think about how team communication and data management will be achieved, including potential platforms required. Project-specific communication platforms may be requested where justified and not already provided through institutional infrastructure.

Ethics and responsible research and innovation (RRI)

What are the ethical and RRI considerations, implications and issues relating to the proposed work? If you do not think that the proposed work raises any ethical or RRI issues, explain why.

What the assessors are looking for in your response

Demonstrate that you have identified and evaluated:

  • the relevant ethical and RRI considerations, including both the research or topic area itself and the design and delivery of the project
  • the wider implications of the proposed work, and how you will maximise the positive societal, environmental, and economic benefits arising from the project, whilst minimising unintended negative impacts, such as research misuse or accidental harm
  • how you will manage these considerations throughout the lifecycle of the project

You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.

Please refer to the UKRI position statement on funding ethical research and Responsible innovation for more information around our expectations on ethical and responsible research and innovation.

Animal involvement and ‘3Rs’

You must complete this section about how your proposed project will involve or impact animals.

If your project does not involve or impact animals, you must confirm this on the next page.

You may be asked about:

  • what animals you are involving
  • the severity of the procedures you are using
  • where the procedures will take place
  • welfare standards you aim to meet
  • the relevance of your project to the development, validation or dissemination of the 3Rs

You may also need to download, complete, and upload at least one set of additional questions. You will be told how to do this towards the end of this section.

To complete this section and check whether your project is in the scope of the questions, refer to the UKRI policy for research and innovation involving animals.

What counts as an animal

UKRI policy relates to all animals in the Kingdom Animalia, including vertebrates and invertebrates.

Genetically modified organisms and biological risk

You must complete this section if your project will include genetically modified organisms or genetic technologies.

If you project does not involve genetically modified organisms or genetic technologies, you must confirm this on the next page.

You may be asked about:

  • the type of organism your project will involve and the procedures your project will include
  • the intended use of the organism or genetic technology
  • the genetic, biological and environmental risks of your project

For more information, see UKRI’s guidance on genetic technologies.

Human participation in health-related research

You must complete this section about whether your project will include human participation.

If your project does not involve human participation, you must confirm this on the next page.

You may be asked about:

  • what type of human participation your project includes
  • the project design for human participation
  • the phase of the clinical trial
  • whether the project will be in an NHS setting, if so, how the project will be registered
  • whether diversity and inclusion will be considered

For more information, see UKRI’s guidance for human participants in research.

Project partners

Add details about any project partners’ contributions. If there are no project partners, you can indicate this on the Funding Service.

A project partner is a collaborating organisation who will have an integral role in the proposed research. This may include direct contributions for example cash, donated equipment and resources, or staff seconded to the project, or indirect and in-kind contributions for example use of project partner’s equipment, datasets, or facilities. Project partners may be in industry, academia, third sector or government organisations in the UK or overseas, including partners based in the EU.

Add the following project partner details:

  • the organisation name and address (searchable via a drop-down list or enter the organisation’s details manually, as applicable)
  • the project partner contact name and email address
  • the type of contribution (direct or indirect) and its monetary value

If a detail is entered incorrectly and you have saved the entry, remove the specific project partner record and re-add it with the correct information.

For audit purposes, UKRI requires formal collaboration agreements to be put in place if an award is made.

Project partners: letters (or emails) of support

Upload a single PDF containing the letters or emails of support from each partner you named in the project partners section. These should be uploaded in English or Welsh only.

What the assessors are looking for in your response

Enter the words ‘attachment supplied’ in the text box, or if you do not have any project partners enter ‘N/A’. Each letter or email you provide should:

  • confirm the partner’s commitment to the project
  • clearly explain the value, relevance, and possible benefits of the work to them
  • describe any additional value that they bring to the project
  • have a page limit of two sides A4 per partner

The Funding Service will provide document upload details when you apply.

If you do not have any project partners, you will be able to indicate this in the Funding Service.

Ensure you have prior agreement from project partners so that, if you are offered funding, they will support your project as indicated in the Project partners section.

For audit purposes, UKRI requires formal collaboration agreements to be put in place if an award is made.

Facilities

Word limit: 600

Does your proposed research require the support and use of a facility?

The ARCHER2 service will end on 21 November 2026, and UKRI is currently transitioning to a new compute landscape. Until details of new compute provision are confirmed, applicants who require HPC resources beyond November 2026 have been advised to select ARCHER2 at application and to describe their compute requirements in full.

Other compute investments to be aware of include:

What the assessors are looking for in your response

If you will need to use a facility, follow your proposed facility’s normal access request procedures. Ensure you have prior agreement so that if you are offered funding, they will support the use of their facility on your project.

For each requested facility you will need to provide the:

  • name of facility, copied and pasted from the facility information list (DOCX, 37KB)
  • proposed usage or costs, or costs per unit where indicated on the facility information list
  • confirmation you have their agreement where required

Facilities should only be named if they are on the facility information list above. If you will not need to use a facility, you will be able to indicate this in the Funding Service.

Host organisation’s support

Word limit: 4,000

Provide details of support from your research organisation.

What the assessors are looking for in your response

Ensure the head of department (or equivalent) of the host organisation provides you with a supporting statement (which they have written), that includes details of any additional support that might add value to the work.

Assessors will be looking for a strong statement of support from your research organisation. This information should have been approved for submission by an appropriate institutional authority.

You must also include the following details:

  • full name
  • their position or role
  • the department, school or institute they lead
  • their contact details

The statement of support provided by your host organisation should be copied and pasted into the text box. You cannot upload the statement of support to this section as an attachment. Your application may be rejected if you upload a host organisation statement of support to the ‘Project partners: letters (or emails) of support’ section or any other section of your application.

Data management and sharing

Word limit: 1,000

How will you manage and share data collected or acquired through the proposed research?

What the assessors are looking for in your response

Provide a data management plan that clearly details how you will comply with UKRI’s published data sharing policy, which includes detailed guidance notes.

Successful outline application

Word limit: 5

Please provide the application reference number for your successful outline application.

Strategic case

Word limit: 1,000

What is the strategic case for your sLoLa project?

What the assessors are looking for in your response

We expect you to:

  • justify the need for sLoLa funding, describing the added value of funding through this mechanism and how the proposed work will demonstrate UK leadership in the field
  • outline a clear strategy for how the research team’s outputs (experiments, data and results) will be fully integrated to deliver ‘greater than sum of parts’ outcomes
  • describe the synergistic benefit of the team science approach to deliver project outcomes which could not be achieved through a series of smaller, shorter grants (for example, BBSRC standard research grants) with individual groups working in isolation
  • explain the significance and importance of the proposed research, including how the sLoLa award will enhance the international position of UK bioscience in the research area
  • explain how the proposed research complements, and does not overlap with, other research funded in this area nationally and internationally including BBSRC’s research portfolio. For information on BBSRC’s portfolio, please see Gateway to Research and downloads on the funding opportunity webpage
  • describe how the research programme will have an impact on the broader health and vitality of UK bioscience. Where applicable, this might include plans for ensuring the longer-term legacy of data, software, technologies or other community resources. This might also include skills and national capability developed during the project or identifying potential routes towards economic or societal impacts where these may already be evident

Management strategy

Word limit: 700 words

How do you plan to manage the sLoLa?

What the assessors are looking for in your response

We expect you to:

  • describe how the project will be managed to ensure effective working of the team, effective utilisation of resources, and successful delivery of the planned outcomes. The management approach should be appropriate to the nature and scale of the programme
  • describe how the project will implement governance and decision-making arrangements appropriate to its scale, complexity and delivery requirements. This may include approaches such as distributed leadership models and inclusive governance that promote meaningful participation across the team.
  • provide details about the project’s management and advisory structure
  • provide information on the proposed membership of the scientific advisory board and how it will be used. A scientific advisory board is required for all projects, which is independent from both the academic institutions and project partners involved in the proposal
  • provide details of the approach to project and risk management, and the monitoring strategy for tracking progress of the proposed programme
  • describe how your approach accounts for people related risks (such as staff turnover, recruitment challenges, or reliance on specialist expertise) and how these are to be mitigated
  • build EDI considerations into the formation, operation and governance of the project, including how these will be operationalised

You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.

Team culture and development

Word limit: 500 words

How will you create an environment where team members can thrive, develop their skills and professional experience, and contribute effectively to the project’s success?

What the assessors are looking for in your response

We expect you to:

  • explain how you will create and maintain an inclusive, collaborative and psychologically safe team culture
  • describe how the project will support the learning, development and wellbeing of all team members throughout the lifetime of the project
  • explain how management and supervisory arrangements will support team members to contribute effectively, take on responsibilities as their careers progress, and receive appropriate recognition for their contributions
  • outline the project’s approach to providing value-added opportunities that enhance the experience and success of team members, such as mentoring, cross-disciplinary collaboration, training, networking, leadership, and wider engagement

This section should be based on tangible and outcome-focused examples, such as:

  • opportunities for development of all team members that sLoLa funding will facilitate
  • intentional design in your team’s ways of working to promote inclusivity
  • your approaches to recognition and credit in a team science context
  • strategies for mentoring and skills development

Scientific advisory board (SAB) members

Word limit: 50

Please provide the name and institution of the proposed SAB members for your project. This information will be used to prevent conflicts in the assessment of your application.

Please see ‘Strategic Advisory Board Guidance’ in Additional information’ under ‘Supporting documents for further information.

Trusted Research and Innovation (TR&I)

Trusted Research and Innovation is the protection of the UK’s intellectual property, sensitive research, people, and infrastructure from potential theft, misuse, and exploitation.

Organisations receiving UKRI funding are obliged to act in line with UK government legislation. They are also expected to undertake appropriate due diligence assessment of organisations involved in research partnerships, collaboration agreements, and commercial contracts.

You will be asked about:

  • which areas of the National Security and Investment (NSI) Act your project relates to
  • who you intend to collaborate with and how
  • if your project requires an export control licence

Your answers may affect the T&Cs of your funding agreement if you are successful. We may use your answers to determine that our current T&Cs are sufficient or if additional T&Cs are required.

How we will assess your application

Assessment process

We will assess your application using the following process.

Full stage will only be open to successful applicants who have been invited to submit following the assessment of their outline application.

Expert review

We will invite experts to review your application independently, against the specified criteria for this funding opportunity.

You will not be able to nominate reviewers for applications on the new UK Research and Innovation (UKRI) Funding Service. Research councils will continue to select expert reviewers.

We are monitoring the requirement for applicant-nominated reviewers as we review policies and processes as part of the continued development of the new Funding Service.

You will have 14 days to respond to reviewers’ comments.

Full stage panel

Following expert review, we will invite experts to use the evidence provided by reviewers and your applicant response to assess the quality of your application. The multidisciplinary panel comprises of outline stage Strategic longer and larger committee (SLC) members and further subject matter experts, including representatives from BBSRC’s responsive mode research committees and BBSRC’s pool of experts.

Following assessment, the committee will provide feedback and recommendations to Biotechnology and Biological Sciences Research Council (BBSRC) of highly rated applications to be considered for funding.

We expect the full stage panel process to take place in May to early June 2027.

Where applications are closely competitive, the Strategic Leadership Committee (SLC) may conduct interviews to support final funding decisions. Interviews will typically involve the project lead and up to three other core team members. Further details will be provided to shortlisted teams in this case.

BBSRC will make the final funding decision.

For more information on how we prioritise applications for funding please visit How we make decisions.

Feedback

BBSRC will not provide additional feedback for all applications following the communication of the outcomes of the applications. Peer review comments will serve as the source of feedback for applicants.

Principles of assessment

We support the San Francisco declaration on research assessment and recognise the relationship between research assessment and research integrity.

Find out about the UKRI principles of assessment and decision making.

Using generative artificial intelligence (AI) in expert review

Generative AI may only be used for the purpose of language refinement during application assessment. When using generative AI to refine the language of a review, expert reviewers and panellists must ensure that:

  • no part of the application being assessed is entered into a generative AI tool
  • no personal information from the application is disclosed
  • generative AI is not tasked with understanding, summarising or evaluating the application’s content

Expert reviewers and panellists must also:

  • comply with relevant intellectual property and data protection legislation
  • not take into account or speculate within their assessment whether generative AI has been used to develop the application

For more detail see our policy on the use of generative AI.

We reserve the right to modify the assessment process as needed.

Assessment areas

The assessment areas we will use are:

  • vision
  • approach
  • applicant and team capability to deliver
  • resources and cost justification
  • ethics and responsible research and innovation (RRI)
  • strategic case
  • management strategy
  • team culture and development

The addition of the team culture and development assessment area aligns with the goals of the UKRI people and teams assessment pilot. Assessors are asked to consider if the people and teams aspects of applications are described adequately and align with the team science approach that underpins the sLoLa scheme. Given the multidisciplinary nature of sLoLa awards, there are enhanced opportunities to support the development of team members, foster inclusive and collaborative working practices, and promote a positive research culture across the wider team.

Find details of assessment questions and criteria under the ‘Application questions’ heading in the ‘How to apply’ section.

Contact details

Get help with your application

If you have a question and the answers aren’t provided on this page

The helpdesk is committed to helping users of the UK Research and Innovation (UKRI) Funding Service as effectively and as quickly as possible. In order to manage cases at peak volume times, the helpdesk will triage and prioritise those queries with an imminent opportunity deadline or a technical issue. Enquiries raised where information is available on the Funding finder opportunity page and should be understood early in the application process (for example, regarding eligibility, content or remit of a funding opportunity) will not constitute a priority case and will be addressed as soon as possible.

Contact details

For help and advice on costings and writing your application please contact your research office in the first instance, allowing sufficient time for your organisation’s submission process.

For questions related to this specific funding opportunity please contact bbsrc.lolagrants@bbsrc.ukri.org

Any queries regarding the system or the submission of applications through the Funding Service should be directed to the helpdesk.

Email: support@funding-service.ukri.org
Phone: 01793 547490

Our phone lines are open:

  • Monday to Thursday 8:30am to 5:00pm
  • Friday 8:30am to 4:30pm

To help us process queries more efficiently, we request that users highlight the council and opportunity name in the subject title of their email query, include the application reference number, and refrain from contacting more than one mailbox at a time.

For further information on submitting an application read How applicants use the Funding Service.

Additional info

Research and innovation impact

Impact can be defined as the long-term intended or unintended effect research and innovation has on society, economy and the environment; to individuals, organisations, and the wider global population.

Webinar for potential applicants

We will hold a webinar on November 2026. This will provide more information about the funding opportunity and a chance to ask questions.

If you are invited to the full stage, you will receive a link to register for the webinar.

Supporting documents

Equality impact assessment (PDF, 197KB)

Project or grant manager guidance (PDF, 429KB)

Strategic advisory board guidance (PDF, 511KB)

BBSRC portfolio of grants over £2 million (PDF, 3MB)

2026 to 27 strategic Longer and Larger (sLoLa) outlines (PDF, 396KB)

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