Funding opportunity

Funding opportunity: MRC: partnership grant: applicant-led

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Apply for funding to support exciting and ambitious partnerships in the remit of the Medical Research Council (MRC).

Partnerships are novel collaborative activities between researchers, to transform our understanding of causes and mechanisms of disease and help accelerate diagnosis, advance treatment and prevent human illness.

You must be employed by an eligible research organisation.

There is no limit to the funding you can apply for, it should be appropriate to the partnership.

MRC will fund 80% of the full economic cost (FEC) and 100% of exceptions.

Funding is available for up to five years.

Questions are now available to indicate a charity co-funder.

Who can apply

This opportunity is open to organisations with standard eligibility. Check if your organisation is eligible.

Who is eligible to apply

To be eligible to apply for this funding opportunity you must:

  • show that you will direct the project and be actively engaged in the work, or contribute to the academic leadership of the partnership
  • demonstrate that you and your team have the right expertise and experience to deliver the aims of the partnership, using interdisciplinary approaches where appropriate

For applicants who do not have a contract of employment for the duration of the proposed project, by submitting an application the research organisation is confirming, if it is successful:

  • contracts will be extended beyond the end date of the project
  • all necessary support for the project and the applicants will be provided, including mentorship and career development for early career researchers

Demand management

You can only be project lead on one application at a time across MRC’s applicant-led responsive funding opportunities (research, partnership and new investigator). If you submit another application while one is being assessed, the new application will be rejected. You should wait until you receive a decision on your current application before submitting another.

Resubmissions

We will not accept uninvited resubmission of applications that were submitted after 1 April 2026 to MRC or the rest of UK Research and Innovation (UKRI). An uninvited resubmission is an application that was previously unsuccessful and has been submitted again without being invited by MRC. This includes applications that are unchanged, minimally revised, or substantially the same as the original submission. Uninvited resubmissions will be rejected.

You should contact us if you are unsure whether your application is a resubmission. Find contacts in the ‘Contact details’ section

Who is not eligible to apply

Partnership grants are not designed to primarily support research. If you would like to apply for funding for a research project, you should instead consider a research grant.

You are also not eligible to apply for this funding opportunity as a project lead if you are based at an international research organisation. This does not include project leads from MRC Unit The Gambia at the London School of Hygiene and Tropical Medicine (LSHTM) or MRC/UVRI (Uganda Virus Research Institute) and LSHTM Uganda Research Unit.

If you are employed by these organisations you cannot apply as project lead or project co-lead, but can participate as project partners on an application led by an eligible UK organisation:

  • businesses
  • charity and third sector organisations

However, charities and third sector organisations that are approved UKRI independent research organisations are eligible to apply as project lead or project co-lead.

International researchers

As MRC is a lead funder for this funding opportunity, international researchers can apply as project co-lead (international).

Project co-leads (international) make a major intellectual contribution to the design or conduct of the project. Their contribution and added value to the research should be clearly explained and justified in the application, see ‘Applicant and team capability to deliver’.

Read the UKRI project co-lead (international) eligibility policy for more details. Please contact us if you are uncertain about eligibility.

You should include all other international collaborators (or UK partners not based at approved organisations) as project partners.

Equality, diversity and inclusion

We are committed to achieving equality of opportunity for all funding applicants. We encourage applications from a diverse range of researchers.

We support people to work in a way that suits their personal circumstances. This includes:

  • career breaks
  • support for people with caring responsibilities
  • flexible working
  • alternative working patterns

UKRI can offer disability and accessibility support for UKRI applicants and grant holders during the application and assessment process.

What we're looking for

Demand management

Demand management is being applied to this funding opportunity. Further details are provided in the ‘Who can apply’ section

Scope

We are looking to fund exciting and ambitious partnerships between a team of researchers carrying out novel collaborative activities or capabilities that add value to high-quality research activities. These can be already supported by existing funding or will underpin future funding within the remit of MRC.

We welcome team-science approaches and multi and interdisciplinary partnerships. You will need to demonstrate that you and your team have the right expertise and experience to deliver the activities. Additionally, details of the support for people and teams should be embedded in the design of your proposal, recognising the importance of supporting staff and the environment they work in.

We fund partnerships working to transform our understanding of human health and causes and mechanisms of disease, to accelerate diagnosis, advance treatment and prevent human illness.

We welcome applications that incorporate global perspectives in partnerships and that have potential to improve global health. Applications involving partners outside the UK should be equitably led and co-designed

Collaborative activities and capabilities can include:

  • networking and partnership activities: establishing multidisciplinary collaborative partnerships or consortia, fostering or enabling a national or international strategy in an area, enabling knowledge sharing or creation across organisations
  • infrastructure support for establishing a unique shared resource or helping to exploit it, for example, staff, systems, equipment, seminars and workshops. This could include networking activities, including outreach work and travel, with a defined output
  • platform activities such as specialist data and software platforms or resources
  • training, career development and capacity building activities in an area of unmet need to support the future delivery of high-value research capabilities
  • funds to support small scale, pump-priming projects may be included but specific research questions should not be the focus of the partnership. Any research projects should be interdisciplinary, high risk or gain projects which will demonstrate the novel capability of a new partnership

This list is not exhaustive. The activity or activities proposed should support the overarching objective of the partnership.

What isn’t in scope:

  • applications that primarily support research. If you would like to apply for funding for a research project, you should instead consider a research grant
  • applications that only request support for networking activities and establishing collaborations without a defined related activity
  • activities that are inward looking, with insufficient openness or engagement with the wider community
  • funding new studentships or fellowships

Please see our case studies for examples of partnership grants and why they were funded by MRC.

You are encouraged to contact us before applying for advice. Applications for partnerships that are out of scope will be rejected. You should email the MRC programme manager relevant to your application. Find contacts in the ‘Contact details’ section.

Duration

We will fund partnerships lasting up to five years.

Projects should start between nine to 18 months after you submit your application.

Sustainability of the partnership beyond the end of the grant should be considered within the proposal. It is only in exceptional circumstances that we would consider requests for renewals or follow on activities.

Funding available

We want to support exciting and ambitious partnerships that will deliver real impact in the field(s) of work. The funds requested should be determined by the ambitions and partnership plans. Resource requests will vary between partnerships, so you are strongly encouraged to discuss this with the relevant programme manager before applying.

There is no limit to the funding you can apply for. Your application must be for an amount that:

  • is appropriate for the partnership
  • you can justify in order to deliver the partnership activities.

We will fund 80% of the full economic cost and 100% of permitted exceptions.

Find out more about full economic costing.

What we will fund

You can request funding for costs such as:

  • a contribution to the salary of the project lead and a small number of co-leads contributing to academic leadership of the partnership
  • support for technical staff
  • consumables
  • equipment or infrastructure that is key to the aims of the partnership or provides a platform for activities associated with the partnership
  • travel costs
  • data preservation, data sharing and dissemination costs
  • estates and indirect costs
  • public partnerships and related activities, including payments to public contributors

You can also request costs for work to be undertaken at international organisations by international project co-leads. We will fund 100% of the eligible costs.

The total of such costs requested for international applicants from high-income countries (those not on the OECD (Organisation for Economic Co-operation and Development) DAC (Development Assistance Committee) List of ODA (Official Development Assistance) Recipients), India and China must not exceed 30% of the total resources requested.

There is no cap on costs requested for international applicants from DAC list countries.

For more information on international costs and what we will and will not fund, see costs we fund and the Collaborate with Researchers in Norway guidance.

What we will not fund

We will not fund:

  • contributions to the salary of co-leads unless critical to academic leadership of the partnership
  • costs primarily for research
  • costs for PhD studentships and fellowships
  • infrastructure only
  • publication costs
  • funding to use as a ‘bridge’ between grants

Project partner

A project partner is a collaborating organisation in the UK or overseas, including partners based in the EU, who will have an integral role in the proposed research. You may include project partners that will support your research project through cash or in-kind contributions, such as:

  • staff time
  • access to equipment
  • sites or facilities
  • the provision of data
  • software or materials
  • recruitment of people, such as research participants
  • providing samples, such as human tissue, for the project

Each project partner must provide a statement of support. If your application involves industry partners, they must provide additional information if the project partner falls within the industry collaboration framework.

Find out more about subcontractors and dual roles.

Who cannot be included as a project partner

Any individual included in your application core team cannot also be a project partner.

Any organisation that employs a member of the application core team cannot be a project partner organisation, this includes other departments within the same organisation.

If you are collaborating with someone in your organisation, consider including them in the core team as project co-lead, or specialist. They cannot be a project partner.

Human participation in research

If the project you are applying for includes a clinical trial, we are looking for you to indicate in the application the clinical trial phase that best reflects the primary objective of the study.  If it does not align with the Phase I-III options, you should select “Other” and provide a brief explanation in the study description.

Clinical trials funded through MRC and UKRI funding opportunities, must be registered with the ISRCTN Registry and receive an ISRCTN number.

Schedule of Events Costs Attribution Tool (SoECAT)

If you are applying to do research in the NHS, public health or social care you usually need to complete a Schedule of Events Cost Attribution Tool (SoECAT). We are looking for evidence you have taken the appropriate steps and for the full costs of your research to be appropriately attributed.

It is important to complete a SoECAT to be eligible for support from the National Institute for Health Research (NIHR) Research Delivery Network (RDN). You must complete a SoECAT even if you don’t think your research will involve excess treatment costs (ETCs).

See MRC guidance on who needs to complete a SoECAT.

SoECAT guidance can be found on the NIHR website.

These are the steps you need to take:

  1. Contact your local attributing the costs of health and social care Research and Development (AcoRD) specialist as early as possible in the application process. They can advise on completing the SoECAT and provide a bespoke service to meet the needs of your study.
  2. Complete an online SoECAT. If you do not have an account for NIHR’s Central Portfolio Management System (CPMS) you will need to create and activate one.
  3. Once your account is created and active, you can complete an online SoECAT by selecting the ‘Apply for a service for a new study’ pathway. Further guidance can be found on the Online SoECAT guidance page.
  4. Request authorisation of your SoECAT.
  5. When you have authorisation, include the ‘funder export’ Excel document from your SoECAT as part of your application in the Human participation in health-related research section.

There are different ways to contact an AcoRD specialist, depending on where you are in the UK:

Contact us about any issues including a SoECAT or AcoRD specialist feedback in your application, such as:

  • your proposed research involves human participation and the NHS, but you don’t think you need a SoECAT, explain why not when you contact us
  • your proposed research involves human participation in Health and Social Care (not NHS), and you think you need a SoECAT

Supporting skills and talent

We encourage you to follow the principles of the Concordat to Support the Career Development of Researchers and the Technician Commitment.

UK Research and Innovation (UKRI) supports over 25,000 full-time equivalent of research and innovation (R&I) staff directly on grants, many more if indirect costs, facility charges and strategic funding streams are included. Those skilled people and teams design our studies, deliver the R&I work and disseminate the outputs. They are the R&I system and mission critical to delivering the outcomes we invest in.

Our expectations for people and teams are collated on the supporting skills and talent section of the good research resource hub.

In this funding opportunity we are piloting a new approach to embedding consideration of people and teams in our assessment. You can find the assessment criteria for integrating support for people and teams in your application (sections; the approach, team capability and resources and costing in the people and teams assessment guidance.

You should evidence a strong commitment to supporting the development of researchers at all stages of their career.

Trusted Research and Innovation (TR&I)

UK Research and Innovation (UKRI) has a long-standing and continuing commitment to supporting and enabling safe and effective collaboration in research and innovation. UKRI is equally committed to ensuring that this takes place with integrity and within strong ethical frameworks.

Our Principles and expectations set out the principles that UKRI applies to TR&I and our general expectations of the research organisations (including businesses, research institutes, and research technical organisations) that we support. Organisations supported by UKRI should be able to provide evidence that their internal controls and processes meet these expectations.

See further guidance and information about TR&I, including where applicants can find additional support.

How to apply

We are running this funding opportunity on the new UK Research and Innovation (UKRI) Funding Service so please ensure that your organisation is registered. You cannot apply on the Joint Electronic Submissions (Je-S) system.

The project lead is responsible for completing the application process on the Funding Service, but we expect all team members and project partners to contribute to the application.

Only the lead research organisation can submit an application to UKRI.

If the lead research organisation is an NHS organisation, check it is available in the Funding Service. You are encouraged to check this early as there may be additional steps for the organisation to be set up before you can apply.

To apply

Three grant types are available, research, new investigator, and partnership. Before you select ‘Start application’, check you are applying for the appropriate grant type. Applications submitted to the incorrect grant type will be rejected.

Select ‘Start application’ near the beginning of this Funding finder page.

  1. Confirm you are the project lead.
  2. Sign in or create a Funding Service account. To create an account, select your organisation, verify your email address, and set a password.
  3. Answer questions directly in the text boxes. You can save your answers and come back to complete them or work offline and return to copy and paste your answers. If we need you to upload a document, follow the upload instructions in the Funding Service. All questions and assessment criteria are listed in the How to apply section on this Funding finder page.
  4. Allow enough time to check your application in ‘read-only’ view before sending to your research office.
  5. Send the completed application to your research office for checking. They will return it to you if it needs editing.
  6. Your research office will submit the completed and checked application to UKRI.

Please be aware that research office and finance teams undertake checks on hosting arrangements and financial eligibility. The ultimate responsibility for ensuring compliance with all opportunity requirements lies with the applicant.

Where indicated, you can also demonstrate elements of your responses in visual form if relevant.

When including images, you must:

  • provide a descriptive caption or legend for each image immediately underneath it in the text box (this must be outside the image and counts towards your word limit)
  • insert each new image on a new line
  • use files smaller than 5MB and in JPEG, JPG, JPE, JFI, JIF, JFIF, PNG, GIF, BMP or WEBP format

Images should only be used to convey important visual information that cannot easily be put into words. The following are not permitted, and your application will be rejected if you include:

  • sentences or paragraphs of text
  • tables
  • excessive quantities of images

A few words are permitted where the image would lack clarity without the contextual words, such as a diagram, where text labels are required for an axis or graph column.

For more guidance on the Funding Service, see:

References

References should be included within the word count of the appropriate question section. You should use your discretion when including references and prioritise those most pertinent to the application.

Hyperlinks can be used in reference information. When including references, you should consider how your references will be viewed and used by the assessors, ensuring that:

  • references are easily identifiable by the assessors
  • references are formatted as appropriate to your research
  • persistent identifiers are used where possible

General use of hyperlinks

Applications should be self-contained. You should only use hyperlinks to link directly to reference information. You must not include links to web resources to extend your application. Assessors are not required to access links to conduct assessment or recommend a funding decision.

Generative artificial intelligence (AI)

Use of generative AI tools to prepare funding applications is permitted, however, caution should be applied.

For more information see our policy on the use of generative AI in application and assessment.

Deadline

We do not have closing dates for applications.  You should simply submit your application when it is ready.

Applications are accepted and processed continuously, so there is no need to focus on a specific deadline.

You may see a notional future closing date displayed in the Funding Service. This is a system requirement and does not reflect an actual deadline. You should ignore this date and submit your application whenever it is ready.

Due to the continuing development of the Funding Service, we will occasionally need to make changes to this funding opportunity to allow technical updates or new policies to be implemented. When updates are required, we will highlight any changes to this funding opportunity on this page. If you are preparing an application, we will contact you and provide an eight week transition period to allow you to complete and submit your application before the current funding opportunity closes, or to apply through the updated funding opportunity.

Following the submission of your application to the funding opportunity, your application cannot be changed by you or us. If there is a problem with an application it will either fail our examination checks and be rejected, or your research organisation may withdraw your application. You would then need to submit a new revised application. Because there are no closing dates you can do this more easily.

Personal data

Processing personal data

MRC, as part of UKRI, will need to collect some personal information to manage your Funding Service account and the registration of your funding applications.

We will handle personal data in line with UK data protection legislation and manage it securely. For more information, including how to exercise your rights, read our privacy notice.

If you apply using the MRC Charity Co-funding Framework, you agree to MRC sharing your personal data with the relevant co-funder(s). This information could include your application, relevant information as part of the assessment process, the award offer letter, and subsequent grant reporting.

Sensitive information

If you or a core team member need to tell us something you wish to remain confidential, email applicantleddiscovery@mrc.ukri.org

Include in the subject line: [the funding opportunity title; sensitive information; your Funding Service application number].

Typical examples of confidential information include:

  • individual is unavailable until a certain date (for example due to parental leave)
  • declaration of interest
  • additional information about eligibility to apply that would not be appropriately shared in the ‘Applicant and team capability’ section
  • conflict of interest for UKRI to consider in reviewer or panel participant selection
  • the application is an invited resubmission

For information about how UKRI handles personal data, read UKRI’s privacy notice.

Institutional matched funding

There is no requirement for matched funding from the institutions hosting the project lead, project co-leads or other staff employed on the application, beyond the standard 20% FEC. Expert reviewers and panels assessing UKRI funding applications must not consider levels of institutional matched funding as a factor on which to base recommendations. Direct and in-kind contributions from third party project partners are encouraged.

This policy does not remove the need for support from host organisations who must provide the necessary research environment and infrastructure for award-specific activities funded by UKRI. For example, research facilities, training and development of staff.

Publication of outcomes

MRC, as part of UKRI, will publish the outcomes of this funding opportunity at board and panel outcomes.

If your application is successful, we will publish some personal information on the UKRI Gateway to Research.

Summary

Word limit: 550

In plain English, provide a summary we can use to identify the most suitable experts to assess your application.

We usually make this summary publicly available on external-facing websites, therefore do not include any confidential or sensitive information. Make it suitable for a variety of readers, for example:

  • opinion-formers
  • policymakers
  • the public
  • the wider research community

Guidance for writing a summary

Clearly describe your proposed work in terms of:

  • context
  • the challenge the project addresses and how tackling this will deliver real impact in the field(s) or area(s)
  • aims and objectives
  • potential applications and benefits

Core team

List the key members of your team and assign them roles from the following:

  • project lead (PL)
  • project co-lead (UK) (PcL)
  • project co-lead (international) (PcL (I))
  • specialist
  • grant manager
  • professional enabling staff
  • research and innovation associate
  • visiting researcher
  • researcher co-lead (RcL)

Only list one individual as project lead. If you include more than one project lead your application will fail at the checking stage.

UKRI has introduced a new addition to the ‘Specialist’ role type. Public contributors such as people with lived experience can now be added to an application.

Find out more about UKRI’s core team roles in funding applications.

Application questions

Vision

Word limit: 750

What are you hoping to achieve with your proposed work?

What the assessors are looking for in your response

Explain how your proposed work:

  • is of excellent quality and importance within or beyond the fields or areas
  • has the potential to advance current understanding, or generate new knowledge, thinking or discovery within or beyond the field or area
  • is timely given current trends, context, and needs
  • impacts world-leading research, society, the economy, or the environment

Within the Vision section we also expect you to:

  • identify the potential direct or indirect benefits and who the beneficiaries might be
  • identify potential improvements in human or population health, whether through contributing to relieving disease or disability burden, improving quality of life or providing benefit to the health service or health-related industry
  • explain the ambition of your vision and how it will improve understanding of causes and mechanisms of human disease
  • explain why establishing a partnership is necessary in this area and how it will add value to the current research landscape

References may be included within this section.

You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.

Approach

Word limit: 3,300

How are you going to deliver your proposed work?

What the assessors are looking for in your response

Explain how you have designed your approach so that it:

  • is effective and appropriate to achieve your objectives
  • is feasible, and comprehensively identifies any risks to delivery and how they will be managed
  • uses a clearly written and transparent methodology (if applicable)
  • summarises the previous work and describes how this will be built upon and progressed (if applicable)
  • will maximise translation of outputs into outcomes and impacts
  • describes how your, and if applicable your team’s, research environment (in terms of the place and relevance to the project) will contribute to the success of the work

Within the Approach section we also expect you to:

  • demonstrate access to the appropriate services, facilities, infrastructure, or equipment to deliver the project
  • provide a project plan including milestones and timelines, in the form of an embedded Gantt chart or similar
  • explain how the partnership will be planned and managed
  • explain how the partnership will enable researchers to work together, network and build capability in a strategic area
  • demonstrate how the partnership will benefit the wider research community
  • if applicable, explain how partnership services, equipment or infrastructure will be accessed by the wider research community
  • outline future plans for sustaining the partnership beyond MRC funding, or for funding research which may develop from the partnership
  • explain and justify the inclusion of public partnerships (if applicable) and the added value these offer
  • describe how you will obtain ethical and regulatory approvals, including the current status of any approvals. Consider the MRC guidance on ethics and approvals
  • explain and justify any involvement of human participants, including participant numbers, characteristics, recruitment methods, the procedures to be undertaken, and their severity
  • explain and justify any use of human tissues or biological samples, including the type of material to be used, quantity required, and its source

References may be included within this section.

You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.

Applicant and team capability to deliver

Word limit: 2,000

Why are you the right individual or team to successfully deliver the proposed work?

What the assessors are looking for in your response

Evidence of how you, and if relevant your team, have:

  • the relevant experience (appropriate to career stage) to deliver the proposed work
  • the right balance of skills and expertise to cover the proposed work
  • the appropriate leadership and management skills to deliver the work and your approach to develop others
  • contributed to developing a positive research environment and wider community

You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.

The word limit for this section is 2,000 words: 1,500 words to be used for Résumé for Research and Innovation (R4RI) modules (including references) and, if necessary, a further 500 words for Additions.

Use the R4RI format to showcase the range of relevant skills you and, if relevant, your team (project and project co-leads, researchers, technicians, specialists, partners and so on) have and how this will help deliver the proposed work. You can include individuals’ specific achievements but only choose past contributions that best evidence their ability to deliver this work. You are encouraged to include ORCID iDs for individuals where relevant, as this can help to demonstrate and verify their achievements.

Complete this section using the R4RI module headings listed. Use each heading once and include a response for the whole team, see the UKRI guidance on R4RI. You should consider how to balance your answer, and emphasise where appropriate the key skills each team member brings:

  • contributions to the generation of new ideas, tools, methodologies, or knowledge, this may include your previous funding and key outputs such as publications
  • the development of others and maintenance of effective working relationships
  • contributions to the wider research and innovation community
  • contributions to broader research or innovation users and audiences and towards wider societal benefit, including public partnerships
Additions

Provide any further details relevant to your application. This section is optional and can be up to 500 words. You should not use it to describe additional skills, experiences, or outputs, but you can use it to describe any factors that provide context for the rest of your R4RI (for example, details of career breaks if you wish to disclose them).

Complete this as a narrative. Do not format it like a CV.

References may be included within this section.

The roles in funding applications policy has descriptions of the different project roles.

Resources and cost justification

Word limit: 1,000

What will you need to deliver your proposed work and how much will it cost?

What the assessors are looking for in your response

Justify the application’s more costly resources, in particular:

  • project staff
  • significant travel for field work or collaboration (but not regular travel between collaborating organisations or to conferences)
  • any equipment that will cost more than £25,000
  • any consumables beyond typical requirements, or that are required in exceptional quantities
  • all facilities and infrastructure costs
  • all resources that have been costed as ‘Exceptions’
  • support for public and patient involvement and engagement. See Payments to public partners
  • support for preserving, long-term storage, or sharing of data
  • support for international co-leads, demonstrating this is within the 30% costs cap for co-leads from high income countries, India and China. There is no cap on costs requested for international applicants from DAC list countries
  • NHS research costs, when they are associated with NHS studies
  • animal costs, such as numbers that need to be bred or maintained and to maintain high welfare standards

Justify why the partnership cannot be supported in any other way than the MRC funding requested.

Justify why each applicant is necessary for the partnership, including their level of time commitment.

You can request costs associated with reasonable adjustments where they increase as a direct result of working on the project. For further information see Disability and accessibility support for UKRI applicants and grant holders. Where a funding limit is imposed on the opportunity, requested costs for reasonable adjustments may exceed the maximum funding amount.

Assessors are not looking for detailed costs or a line-by-line breakdown of all project resources. Overall, they want you to demonstrate how the resources you anticipate needing for your proposed work:

  • are comprehensive, appropriate, and justified
  • represent the optimal use of resources to achieve the intended outcomes
  • maximise potential outcomes and impacts

Ethics and responsible research and innovation (RRI)

What are the ethical and RRI considerations, implications and issues relating to the proposed work? If you do not think that the proposed work raises any ethical or RRI issues, explain why.

What the assessors are looking for in your response

Demonstrate that you have identified and evaluated:

  • the relevant ethical and RRI considerations, including both the research or topic area itself and the design and delivery of the project
  • the wider implications of the proposed work, and how you will maximise the positive societal, environmental, and economic benefits arising from the project, whilst minimising unintended negative impacts, such as research misuse or accidental harm
  • how you will manage these considerations throughout the lifecycle of the project

Please refer to the UKRI position statement on funding ethical research and Responsible innovation for more information around our expectations on ethical and responsible research and innovation.

Animal involvement and ‘3Rs’

You must complete this section about how your proposed project will involve or impact animals.

If your project does not involve or impact animals, you must confirm this on the next page.

You may be asked about:

  • what animals you are involving
  • the severity of the procedures you are using
  • where the procedures will take place
  • welfare standards you aim to meet
  • the relevance of your project to the development, validation or dissemination of the 3Rs

You may also need to download, complete, and upload at least one set of additional questions. You will be told how to do this towards the end of this section.

To complete this section and check whether your project is in the scope of the questions, refer to the UKRI policy for research and innovation involving animals.

What counts as an animal

UKRI policy relates to all animals in the Kingdom Animalia, including vertebrates and invertebrates.

Genetically modified organisms and biological risk

You must complete this section if your project will include genetically modified organisms or genetic technologies.

If your project does not involve genetically modified organisms or genetic technologies, you must confirm this on the next page.

You may be asked about:

  • the type of organism your project will involve and the procedures your project will include
  • the intended use of the organism or genetic technology
  • the genetic, biological and environmental risks of your project

For more information, see UKRI’s guidance on genetic technologies.

Human participation in health-related research

You must complete this section about whether your project will include human participation.

If your project does not involve human participation, you must confirm this on the next page.

You may be asked about:

  • what type of human participation your project includes
  • the project design for human participation
  • the phase of the clinical trial
  • whether the project will be in an NHS setting, if so how the project will be registered
  • whether diversity and inclusion will be considered

For more information, see UKRI’s guidance for human participants in research.

Data management and sharing

Word limit: 1,500

How will you manage and share data collected or acquired through the proposed research?

What the assessors are looking for in your response

Provide a data management plan which should clearly detail how you will comply with MRC’s published data management and sharing policies, which includes detailed guidance notes.

Provide your response in the text box following the headings in the MRC data management plan template. You are not required to upload the document to your application.

The length of your plan will vary depending on the type of study being undertaken, as follows:

  • population cohorts, longitudinal studies, genetic, omics and imaging data, biobanks, and other collections that are potentially a rich resource for the wider research community: maximum of 1,500 words
  • all other research, less complex, the plan may be as short as 500 words

Facilities

Word limit: 250

Does your proposed research require the support and use of a facility?

The ARCHER2 service will end on 21 November 2026, and UKRI is currently transitioning to a new compute landscape. Until details of new compute provision are confirmed, applicants who require HPC resources beyond November 2026 have been advised to select ARCHER2 at application and to describe their compute requirements in full.

Other compute investments to be aware of include:

What the assessors are looking for in your response

If you will need to use a facility, follow your proposed facility’s normal access request procedures. Ensure you have prior agreement so that if you are offered funding, they will support the use of their facility on your project.

For each requested facility you will need to provide the:

  • name of facility, copied and pasted from information list
  • confirmation you have their agreement where required

Facilities should only be named if they are on the facility information list above. If you will not need to use a facility, you will be able to indicate this in the Funding Service.

Project partners

Add details about any project partners contributions. If there are no project partners, you can indicate this on the Funding Service.

A project partner is a collaborating person or organisation who will have an integral role in your proposed research. This may include direct contributions for example cash, donated equipment and resources, or staff seconded to the project, or indirect and in-kind contributions for example use of project partner’s equipment, datasets, or facilities. Project partners may be in industry, academia, third sector or government organisations in the UK or overseas, including partners based in the EU.

A project partner is not anyone in your core team or anyone from your organisation or any of the other organisations represented by core team members.

Add the following project partner details:

  • the organisation name (searchable via a drop-down list or enter the organisation’s details manually, as applicable)
  • the project partner contact name and email address
  • the type of contribution (direct or in-direct) and its monetary value

If a detail is entered incorrectly and you have saved the entry, remove the specific project partner record and re-add it with the correct information.

If there are specific circumstances where project partners do require funding for minor costs such as travel and subsistence, these project partner costs should be claimed and justified within the resources and costs section of your application.

Important information

If you are adding a project partner to this section, you must ensure they provide you with a letter or email of support and you upload it to ‘Project partners: letters or emails of support’.

If your project partners are from industry or a company, you must also complete the ‘Industry Collaboration Framework (ICF)’ section.

Project partners responsible for carrying out animal work

If the project partner is responsible for conducting animal work or providing animals or animal tissue samples, you must ensure that you complete and upload the appropriate forms under the ‘Animal involvement and ‘3Rs’’ section (if applicable).

For audit purposes, UKRI requires formal collaboration agreements to be put in place if an award is made.

Project partners: letters (or emails) of support

Word limit: 10

Upload a single PDF containing the letters or emails of support from each partner you named in the ‘Project partners’ section. These should be uploaded in English or Welsh only.

What the assessors are looking for in your response

If you do not have any project partners, you will be able to indicate this in the Funding Service.

What supporting statements we are looking for

We are looking for you to provide letters or emails of support from all your identified project partners.

What we are not looking for

We don’t want any other letters (or emails) of support, from people who are not your identified project partners, such as those simply expressing general support for your project. If these are included by you, they will be ignored by us and will not be used in the assessment process.

Important information

You should only provide letters or emails of support from people you have identified in the project partner section of your application, who will have an integral role in your proposed research.

What each project partner letter or email of support must include

Each project partner letter or email you provide should:

  • include the name of the project partner organisation and contact information
  • explain the project partners’ commitment to the project
  • explain the value, relevance, and possible benefits of the proposed work, to them
  • describe any additional value they will bring to the project
  • not exceed two sides of A4 per project partner

Project partner letters and emails of support are not required to be on headed paper or include handwritten signatures (electronic signatures are acceptable).

The Funding Service will provide document upload details when you apply.

Project partners from industry or a company

Industry or company project partners are required to download and complete the industry or company letter of support template. You must also complete the ‘Industry Collaboration Framework (ICF)’ section. Find out more about ICF.

Project partners responsible for recruiting research participants or providing human tissue or samples

If the project partner is responsible for the recruitment of people as research participants or providing human tissue, their letter or email of support should include:

  • agreement that the project partner will recruit the participants or provide tissue
  • confirmation that what is being supplied is suitable for the proposed work
  • confirmation that the quantity of tissue being supplied is suitable, but not excessive for achieving meaningful results (if applicable)
Agreement with your project partners

Ensure you have prior agreement from project partners so that, if you are offered funding, they will support your project as indicated in the ‘Project partners’ section.

For audit purposes, UKRI requires formal collaboration agreements to be put in place if an award is made.

Industry Collaboration Framework (ICF)

Word limit: 1,500

Does your application include collaboration with industry or company project partners?

What the assessors are looking for in your response

The assessors are looking for you to confirm if your proposed work involves collaboration with an industry or company project partner. If it does, you will need to follow the MRC ICF.

By ‘industry or company’ we mean an enterprise that puts or has intention to put goods or services on a market.

For guidance to assist your decision if your proposed work requires you to follow ICF, you should explore the ICF decision tree and find out more about ICF which includes:

  • collaboration agreements
  • definitions of basic or applied research
  • internationally based companies
  • subsidy control
  • intellectual property (IP) arrangements
  • fully flexible and gated contributions
  • the ICF assessment criteria

Enter ‘Yes’ in the text box if you have industry or company project partners and you are likely to follow ICF. You should also confirm your answers to the ICF questions one to nine in the text box for each ICF project partner.

Contact us if you are unsure if your application should follow ICF. Find contacts in the ‘Contact details’ section.

In addition to the project partner information completed in the previous section, the assessors are looking for information relating to the nature, goals and conditions of the collaboration and any restrictions or rights to the project results that could be claimed by the industry or company project partner.

Confirm your answers to the ICF questions in the text box, repeat this process for each ICF project partner:

  1. Name the industry or company project partner considered under ICF.
  2. Indicate whether your application is basic research or applied research.
  3. Explain why, in the absence of the requested UKRI funding, the collaboration and the planned research could not be undertaken.
  4. State whether your application is under the category of fully flexible contribution or gated contribution (based on the IP sharing arrangements with the industry or company partner).
  5. Outline the pre-existing IP (‘background IP’) that each partner, including the academic partner, will bring to the collaborative research project and the terms under which partners may access these assets.
  6. Outline the IP that is expected to be developed during the collaborative research project (‘foreground IP’) and briefly outline how it will be managed, including:
    • who will own this IP
    • what rights industry or company partners will have to use academically-generated foreground IP during and after the research project, for internal research and development or for commercial purposes
    • any rights of the academic partner to commercialise the foreground IP, including foreground IP generated by industry or company partners
  7. Outline any restrictions to dissemination of the project results, including the rights of the industry or company partner to:
    • review, approve or delay publications (including the time period associated with such rights)
    • request or require the removal of any information
  8. Declare any conflicts of interest held by the applicants in relation to the industry or company project partners and describe how they will be managed.
  9. Justify collaborating with an overseas industry or company under ICF (if applicable).

Failure to provide the information requested for industry or company partners under ICF could result in your application being rejected.

You are recommended to discuss the goals and conditions of any collaboration with an industry or company with your technology transfer or contracts office before applying.

For audit purposes, UKRI requires formal collaboration agreements to be put in place if an award is made. You must provide us with a copy of the collaboration agreement, signed by all partners, before an ICF award starts.

If this does not apply to your proposed work, you will be able to indicate this in the Funding Service

Related applications

Word limit: 2,000

Is this application related to another application to MRC or other funding organisation?

What the assessors are looking for in your response

If your application is not related to another, you will be able to indicate this in the Funding Service.

If your application is related to another, state your previous reference number and explain how this new application is related to the other application.

If the related application was submitted to another funder you should identify the name of the funder and when you applied.

Resubmissions

Going forward, we will not accept uninvited resubmission of unsuccessful applications that were submitted after 1 April 2026 to MRC or the rest of UKRI. Uninvited resubmissions will be rejected.

If your unsuccessful application was submitted before 1 April 2026 follow our previous policy, this means you may resubmit it after waiting 12 months. Early resubmissions will be rejected.

Where relevant confirm the details of your previous application or invitation to resubmit and describe how this application differs from the previous application and how feedback on the previous application has been considered and acted on. If you are resubmitting an application that previously allowed a higher word count, you may include additional detail in this section.

Duplicate submissions

You can only apply to us at the same time as another funder to support the same work if they are outside UKRI, also allow this and the application is time sensitive. You must explain the time sensitivity of the proposed research based on its urgency or feasibility and justify why a duplicate submission is necessary. The end of a grant or contract is not considered justification for duplicate submission. If there isn’t a clearly justified time sensitive research need your application will be rejected. For more information see submitting your application

Charity co-funders

Word limit: 10

Provide the name of the charity organisation that has agreed to co-fund this application.

What assessors are looking for in your response

If you are not applying for a charity co-funded grant, you will be able to indicate this in the Funding Service.

Co-funding must be discussed with, and agreed by, the charity co-funder before submission. Refer to the MRC Charity Co-funding Framework  guidance for details of the process and a list of participating charity co-funders. If the charity is not listed, contact partnership@mrc.ukri.org so we may confirm eligibility.

Only name a charity co-funder where prior agreement has been obtained. Applications naming a co-funder that has not agreed to contribute before submission will not be considered for co-funding.

You must provide the charity co-funder’s contribution within the next section.

By applying using the MRC Charity Co-funding Framework, you agree to MRC sharing your personal data with the relevant co-funder(s). This information could include your application, relevant information as part of the assessment process, the award offer letter, and subsequent grant reporting.

For more information, including how to exercise your rights, read our privacy notice.

Charity co-funder’s contribution

Word limit: 1

What percentage contribution has the charity co-funder agreed to provide?

What assessors are looking for in your response

If you are not applying for a charity co-funded grant, you will be able to indicate this in the Funding Service.

Only complete this section where the co-funder has confirmed a contribution before submission.

Provide the indicative percentage contribution agreed by the charity co-funder.

International agreements

Word limit: 50

Is your application using an international agreement?

What assessors are looking for in your response

If your application is not using an international agreement, enter ‘N/A’ in the text box.

If your application is using an international agreement, identify the agreement concerned by answering ‘Yes’ followed by ‘FAPESP’ or ‘FNR’ or ‘RCN’:

  • lead agency agreement with Luxembourg (FNR)
  • lead agency agreement with Sao Paulo Research Foundation (FAPESP)
  • Collaborate with researchers in Norway (RCN)
Lead agency agreements

For applications using a lead agency agreement the assessors are looking for you to create and upload the required lead agency documents, to support your application. You must complete all the relevant documentation and attach it to this application as a single PDF. This is not required for applications using the Collaborate with researchers in Norway agreement.

FAPESP

FAPESP applicants must complete the FAPESP-specific forms.

Documents and guidance are available on the FAPESP website, including the FAPESP proposal forms. The proposal form should include:

  • consolidated budget form
  • letter of eligibility
FNR

FNR applicants should complete the FNR-specific forms.

Documents and guidance are available on the FNR website, including:

  • INTER budget sheet
  • INTER budget justification
  • INTER budget plan
  • FNR eligibility letter of support

You must also complete the ‘Project partners’ section, with information about the international research partner, including:

  • international lead applicant contact name and organisation details
  • contribution from the international funder (FAPESP or FNR)

Include the experience, skills and contributions of your international research partners in the response to ‘Applicant and team capability to deliver’.

You should ensure that you have read and understood the specific requirements for the lead agency agreement you are applying to, especially for costing the applications. Failure to comply with the specific guidance may result in the rejection of your application.

On receipt of your application, we will provide the international funder (FAPESP or FNR) with a copy to complete eligibility checks and provide names of expert reviewers.

For general FAPESP guidance please see the FAPESP website.

For general FNR guidance please see the FNR website.

Collaborate with researchers in Norway

There are no additional documents, complete the application as normal requesting all the required resources and costs and include the Norway-based researcher as a project co-lead (international).

See further guidance, including the costs the MRC will cover.

If this does not apply to your proposed work, you will be able to indicate this in the Funding Service.

Keywords

Word limit: 10

Provide up to five keywords that describe your application.

What the assessors are looking for in your response

Provide up to a maximum of five keywords including the health area, for example, mental health, engineering biology, environmental health, diagnosis, obesity, vaccine development.

Use commas or spaces to distinguish individual terms or phrases.

This is for administrative purposes to help with the initial application processing and will not affect the overall assessment or influence the outcome of your application.

Trusted Research and Innovation (TR&I)

Trusted Research and Innovation is the protection of the UK’s intellectual property, sensitive research, people, and infrastructure from potential theft, misuse, and exploitation.

Organisations receiving UKRI funding are obliged to act in line with UK government legislation. They are also expected to undertake appropriate due diligence assessments of organisations involved in research partnerships, collaboration agreements, and commercial contracts.

You will be asked about:

  • which areas of the National Security and Investment (NSI) Act your project relates to
  • who you intend to collaborate with and how
  • if your project requires an export control licence

Your answers may affect the T&Cs of your funding agreement if you are successful. We may use your answers to determine that our current T&Cs are sufficient or if additional T&Cs are required.

How we will assess your application

Assessment process

We will assess your application using the following process.

Examination of applications

All applications will be examined to ensure they meet the eligibility criteria and scope of the funding opportunity. If your application is outside the scope, you will be advised by email, and we will not assess your application.

Shortlisting

First your application will be assessed by members of our college of experts. Then a shortlisting panel from the college of experts will decide which applications continue to the next stage of assessment. This will be based on the ambition, expected impact and deliverability of your application, only those applications that best meet these criteria will be shortlisted.

If your application is not shortlisted it is unsuccessful.

Shortlisting decision meetings will take place twice a year, or more frequently depending on application numbers.

We aim to communicate decisions within 10 days of the shortlisting panel meeting.

Expert review

If your application is shortlisted it moves to the expert review stage and we will invite experts to review your application independently, against the specified criteria for this funding opportunity.

You will have 14 days to respond to reviewers’ comments.

Interview

The next stage of assessment is an interview. A panel from the college of experts will conduct interviews with applicants (project lead and up to two co-leads) after which the panel will score and prioritise your application.

We will contribute towards the cost of your return travel to attend the interview, modest subsistence costs and reasonable additional family care costs. We will endeavour to offer virtual interviews if required.

We expect interviews to take place twice a year, usually in November and May.

Funding decision meeting

Following shortlisting, expert review and interview, panel chairs and MRC Executives will make the funding decision. Funding decision meetings will take place twice a year, shortly after the interview panels.

See more information on how we prioritise applications for funding and the MRC place framework.

Timescale

Do not contact us to ask about the progress of your application. The time from submission to decision will vary depending on when you apply and if your application is shortlisted for interview. If your application is unsuccessful at shortlisting, you will receive a decision more quickly, usually within three to five months.

We encourage applicants to submit their strongest, highest quality application when it is ready. Consider our demand management approach, which means that each project lead may have only one application being assessed at a time within these opportunities. Applications that are unsuccessful cannot be resubmitted unless MRC invites a resubmission in exceptional circumstances.

Feedback

If your application is not shortlisted, we will give you panel feedback to explain why it was not shortlisted. Feedback will be sent separately after your application is confirmed as unsuccessful, it will be emailed to you within six weeks of the shortlisting panel.

Applicants that reach the second stage of assessment will receive expert reviewer comments as their primary form of feedback.

Applicants that are unsuccessful following an interview may receive additional feedback from the interview process, including key issues informing or influencing the funding decision.

Principles of assessment

We support the San Francisco declaration on research assessment and recognise the relationship between research assessment and research integrity.

Find out about the UKRI principles of assessment and decision making.

Using generative artificial intelligence (AI) in expert review

Generative AI may only be used for the purpose of language refinement during application assessment. When using generative AI to refine the language of a review, expert reviewers and panellists must ensure that:

  • no part of the application being assessed is entered into a generative AI tool
  • no personal information from the application is disclosed
  • generative AI is not tasked with understanding, summarising or evaluating the application’s content

Expert reviewers and panellists must also:

  • comply with relevant intellectual property and data protection legislation
  • not take into account or speculate within their assessment whether generative AI has been used to develop the application

For more detail see our policy on the use of generative AI.

We reserve the right to modify the assessment process as needed.

Assessment areas

The assessment areas we will use at shortlisting are:

  • ambition of the vision
  • potential impact of the research
  • deliverability of the proposed work

For more information see Shortlisting assessment process (PDF, 137KB).

The assessment areas we will use at expert review and interview are:

  • vision of the project
  • approach to the project (including data management)
  • capability of the applicant or applicants and the project team to deliver the project
  • resources requested to do the project
  • ethical and responsible research and innovation considerations of the project

In this funding opportunity we are piloting a new approach to embedding consideration of people and teams in our assessment. Please refer to the people and teams assessment guidance when completing your application.

Find details of assessment questions and criteria under the ‘Application questions’ heading in the ‘How to apply’ section.

Contact details

Get help with your application

If you have a question and the answers aren’t provided on this page.

The helpdesk is committed to helping users of the UK Research and Innovation (UKRI) Funding Service as effectively and as quickly as possible. In order to manage cases at peak volume times, the helpdesk will triage and prioritise those queries with an imminent opportunity deadline or a technical issue. Enquiries raised where information is available on the Funding finder opportunity page and should be understood early in the application process (for example, regarding eligibility, content or remit of a funding opportunity) will not constitute a priority case and will be addressed as soon as possible.

Contact details

For help and advice on costings and writing your application please contact your research office in the first instance, allowing sufficient time for your organisation’s submission process.

For questions related to remit and scientific aspects of this specific funding opportunity email the relevant MRC programme manager:

For any other questions related to this specific funding opportunity email: applicantleddiscovery@mrc.ukri.org

For general questions related to MRC funding including our funding opportunities and policy email: rfpd@mrc.ukri.org

Any queries regarding the system or the submission of applications through the Funding Service should be directed to the helpdesk.

Email: support@funding-service.ukri.org

Phone: 01793 547490

Our phone lines are open:

  • Monday to Thursday 8:30am to 5:00pm
  • Friday 8:30am to 4:30pm

To help us process queries more efficiently, we request that users highlight the council and opportunity name in the subject title of their email query, include the application reference number, and refrain from contacting more than one mailbox at a time.

For further information on submitting an application read How applicants use the Funding Service.

Additional info

Background

International agreements

You can apply for this funding opportunity using these lead agency agreements:

You should check the requirements for the agreement you are using and submit the joint application to the international funder within seven days after your submission to the MRC.

You can apply for this funding opportunity using this international agreement: Collaborate with researchers in Norway.

Supporting documents

Shortlisting assessment process (PDF, 137KB)

Research and innovation impact

Impact can be defined as the long-term intended or unintended effect research and innovation has on society, economy and the environment; to individuals, organisations, and the wider global population.

This is the website for UKRI: our seven research councils, Research England and Innovate UK. Let us know if you have feedback or would like to help improve our online products and services.