We are running this funding opportunity on the new UK Research and Innovation (UKRI) Funding Service so please ensure that your organisation is registered. You cannot apply on the Joint Electronic Submissions (Je-S) system.
Pre-application stage
You must contact us before you apply to check if your application is suitable. You can do this at any time, and we encourage you to contact us as early as possible. The latest we will consider a pre-application for this opportunity is 7 July 2025.
When you contact us attach a brief description of your application. The document may be up to four pages, including two pages outlining the proposed partnership, one page for the track record of your team and up to one page of references.
The document should include:
- the title of the potential partnership
- the project lead and co-leads and their organisations
- your collaborators (if known at this stage)
- an estimate of the likely cost to MRC, including staff and equipment
You should explain the aims of the partnership, including:
- why the partnership is important
- the nature of the partnership and its activities
- how these activities align with the partnership grant scope
You should explain your and your team’s track record and show you have the potential to successfully manage and deliver the partnership, based on your research track record, outputs and funding history.
Send your pre-application to the relevant MRC board team, see the ‘Contact details’ section for more information.
Full application stage
The project lead is responsible for completing the application process on the Funding Service, but we expect all team members and project partners to contribute to the application.
Only the lead research organisation can submit an application to UKRI.
If the lead research organisation is an NHS organisation, check it is available in the Funding Service. You are encouraged to check this early as there may be additional steps for the organisation to be set up before you can apply.
To apply
Four grant types are available, research, new investigator, programme and partnership. Before you select ‘Start application’, check you are applying for the appropriate grant type. Applications submitted to the incorrect grant type will be rejected.
Select ‘Start application’ near the beginning of this Funding finder page.
- Confirm you are the project lead.
- Sign in or create a Funding Service account. To create an account, select your organisation, verify your email address, and set a password. If your organisation is not listed, email support@funding-service.ukri.org
Please allow at least 10 working days for your organisation to be added to the Funding Service. We strongly suggest that if you are asking UKRI to add your organisation to the Funding Service to enable you to apply to this opportunity, you also create an organisation Administration Account. This will be needed to allow the acceptance and management of any grant that might be offered to you.
- Answer questions directly in the text boxes. You can save your answers and come back to complete them or work offline and return to copy and paste your answers. If we need you to upload a document, follow the upload instructions in the Funding Service. All questions and assessment criteria are listed in the How to apply section on this Funding finder page.
- Allow enough time to check your application in ‘read-only’ view before sending to your research office.
- Send the completed application to your research office for checking. They will return it to you if it needs editing.
- Your research office will submit the completed and checked application to UKRI.
Where indicated, you can also demonstrate elements of your responses in visual form if relevant.
When including images, you must:
- provide a descriptive caption or legend for each image immediately underneath it in the text box (this must be outside the image and counts towards your word limit)
- insert each new image onto a new line
- use files smaller than 5MB and in JPEG, JPG, JPE, JFI, JIF, JFIF, PNG, GIF, BMP or WEBP format
Images should only be used to convey important visual information that cannot easily be put into words. The following are not permitted, and your application may be rejected if you include:
- sentences or paragraphs of text
- tables
- excessive quantities of images
A few words are permitted where the image would lack clarity without the contextual words, such as a diagram, where text labels are required for an axis or graph column.
Watch our research office webinars about the Funding Service.
For more guidance on the Funding Service, see:
References
References should be included within the word count of the appropriate question section. You should use your discretion when including references and prioritise those most pertinent to the application.
Hyperlinks can be used in reference information. When including references, you should consider how your references will be viewed and used by the assessors, ensuring that:
- references are easily identifiable by the assessors
- references are formatted as appropriate to your research
- persistent identifiers are used where possible
General use of hyperlinks
Applications should be self-contained. You should only use hyperlinks to link directly to reference information. You must not include links to web resources to extend your application. Assessors are not required to access links to conduct assessment or recommend a funding decision.
Generative artificial intelligence (AI)
Use of generative AI tools to prepare funding applications is permitted, however, caution should be applied.
For more information see our policy on the use of generative AI in application and assessment.
Deadline
MRC must receive your application by 4 September 2025 at 4:00pm UK time.
You will not be able to apply after this time.
Make sure you are aware of and follow any internal institutional deadlines.
Following the submission of your application to the funding opportunity, your application cannot be changed, and applications will not be returned for amendment. If your application does not follow the guidance, it may be rejected.
Personal data
Processing personal data
MRC, as part of UKRI, will need to collect some personal information to manage your Funding Service account and the registration of your funding applications.
We will handle personal data in line with UK data protection legislation and manage it securely. For more information, including how to exercise your rights, read our privacy notice.
Sensitive information
If you or a core team member need to tell us something you wish to remain confidential, email the relevant MRC team:
Infections and immunity board: iib@mrc.ukri.org
Molecular and cellular medicine board: mcmb@mrc.ukri.org
Neurosciences and mental health board: nmhb@mrc.ukri.org
Population and systems medicine board: psmb@mrc.ukri.org
Include in the subject line: [the funding opportunity title; sensitive information; your Funding Service application number].
Typical examples of confidential information include:
- individual is unavailable until a certain date (for example due to parental leave)
- declaration of interest
- additional information about eligibility to apply that would not be appropriately shared in the ‘Applicant and team capability’ section
- conflict of interest for UKRI to consider in reviewer or panel participant selection
- the application is an invited resubmission
For information about how UKRI handles personal data, read UKRI’s privacy notice.
Publication of outcomes
MRC, as part of UKRI, will publish the outcomes of this funding opportunity at board and panel outcomes.
If your application is successful, we will publish some personal information on the UKRI Gateway to Research.
Summary
Word limit: 550
In plain English, provide a summary we can use to identify the most suitable experts to assess your application.
We usually make this summary publicly available on external-facing websites, therefore do not include any confidential or sensitive information. Make it suitable for a variety of readers, for example:
- opinion-formers
- policymakers
- the public
- the wider research community
Guidance for writing a summary
Clearly describe your proposed work in terms of:
- context
- the challenge the project addresses
- aims and objectives
- potential applications and benefits
Core team
List the key members of your team and assign them roles from the following:
- project lead (PL)
- project co-lead (UK) (PcL)
- project co-lead (international) (PcL (I))
- specialist
- grant manager
- professional enabling staff
- research and innovation associate
- visiting researcher
- researcher co-lead (RcL)
Only list one individual as project lead. If you include more than one project lead your application will fail at the checking stage.
UKRI has introduced a new addition to the ‘Specialist’ role type. Public contributors such as people with lived experience can now be added to an application.
Find out more about UKRI’s core team roles in funding applications.
Application questions
MRC research board
Which MRC research board is most relevant to your application?
Word limit: 1
Select one MRC research board your application most closely aligns to.
Copy one acronym corresponding to your selected board and paste into the text box:
- Infections and Immunity Board (IIB)
- Molecular and Cellular Medicine Board (MCMB)
- Neuroscience and Mental Health Board (NMHB)
- Population and Systems Medicine Board (PSMB)
Additional guidance
This is for administrative purposes to help with the initial application processing. We will check your choice and make a final decision on which board will lead the assessment of your application.
MRC research area
Word limit: 1
Select the primary MRC research area your application most closely aligns to.
In the text box, copy the number corresponding to your selected area:
Infections and immunity board
1. bacterial disease and host response to bacterial pathogens
2. fungal disease and host response to fungal pathogens
3. parasitic disease and host response to parasitic pathogens
4. viral disease and host response to viral pathogens
5. immune disease and immunology
6. vaccinology
Molecular and cellular medicine board
7. cancer
8. cell biology
9. clinical pharmacology
10. developmental biology
11. environment and health
12. genetics and genomics
13. advanced therapies and regenerative medicine
14. haematology
15. structural biology
16. toxicology
17. chemical biology
Neuroscience and mental health board
18. neuronal cell biology and signalling
19. cognition and higher functions
20. developmental neurobiology
21. mental health and addiction
22. neurology and neurodegeneration
23. neurophysiology of systems
24. pain, sleep and fatigue
25. sense disorders
26. clinical neurology and imaging
27. cognitive and behavioural neuroscience
Population and systems medicine board
28. cardiovascular medicine
29. gastroenterology
30. dentistry and orofacial medicine
31. dermatology
32. inflammation
33. endocrinology
34. metabolism and metabolic disease
35. musculoskeletal
36. nutrition
37. obesity
38. population health
39. longitudinal population studies
40. reproductive health
41. maternal health including pregnancy and childbirth
42. renal function and disease
43. respiratory
44. hepatic function and disease
45. paediatrics and child health
46. ageing
47. multimorbidity
48. rare diseases
49. trauma
Cross-board areas
50. integrated understanding of human physiology and disease
51. motor neurone disease
52. myalgic encephalomyelitis or chronic fatigue syndrome
Additional guidance
This is for administrative purposes to help with the initial application processing. We will check your choice and make a final decision on which board will lead the assessment of your application.
MRC grant type
Word limit: 100
Why does your proposed work need partnership type funding?
What the assessors are looking for in your response
Explain how your proposed work is a novel partnership and why it needs funding for collaborative activities or capabilities.
Within this section we also expect you to:
- confirm you have completed the mandatory pre-application stage for this funding opportunity
- name the MRC programme manager who agreed that this application could be submitted
Vision
Word limit: 550
What are you hoping to achieve with your proposed work?
What the assessors are looking for in your response
Explain how your proposed work:
- is of excellent quality and importance within or beyond the fields or areas
- has the potential to advance current understanding, or generate new knowledge, thinking or discovery within or beyond the field or area
- is timely given current trends, context, and needs
- impacts world-leading research, society, the economy, or the environment
Within the Vision section we also expect you to:
- identify the potential direct or indirect benefits and who the beneficiaries might be
- identify potential improvements in human or population health, whether through contributing to relieving disease or disability burden, improving quality of life or providing benefit to the health service or health-related industry
- explain why establishing a partnership is necessary in this area and how it will add value to the current research landscape
References may be included within this section.
You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.
Approach
Word limit: 5,500
How are you going to deliver your proposed work?
What the assessors are looking for in your response
Explain how you have designed your approach so that it:
- is effective and appropriate to achieve your objectives
- is feasible, and comprehensively identifies any risks to delivery and how they will be managed
- uses a clearly written and transparent methodology (if applicable)
- summarises the previous work and describes how this will be built upon and progressed (if applicable)
- will maximise translation of outputs into outcomes and impacts
- describes how your, and if applicable your team’s, research environment (in terms of the place and relevance to the project) will contribute to the success of the work
Within the Approach section we also expect you to:
- demonstrate access to the appropriate services, facilities, infrastructure, or equipment to deliver the project
- provide a project plan including milestones and timelines, in the form of an embedded Gantt chart or similar
- explain how the partnership will be planned and managed
- explain how the partnership will enable researchers to work together, network and build capability in a strategic area
- demonstrate how the partnership will benefit the wider research community
- if applicable, explain how partnership services, equipment or infrastructure will be accessed by the wider research community
- outline future plans for sustaining the partnership beyond MRC funding, or for funding research which may develop from the partnership
- explain and justify the inclusion of public partnerships (if applicable) and the added value these offer
References may be included within this section.
You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.
Data management and sharing
Word limit: 1,500
How will you manage and share data collected or acquired through the proposed research?
What the assessors are looking for in your response
Provide a data management plan which should clearly detail how you will comply with MRC’s published data management and sharing policies, which includes detailed guidance notes.
Provide your response in the text box following the headings in the MRC data management plan template. You are not required to upload the document to your application.
The length of your plan will vary depending on the type of study being undertaken:
- population cohorts; longitudinal studies; genetic, omics and imaging data; biobanks, and other collections that are potentially a rich resource for the wider research community: maximum of 1,500 words
- all other research, less complex, the plan may be as short as 500 words
Applicant and team capability to deliver
Word limit: 1,650
Why are you the right individual or team to successfully deliver the proposed work?
What the assessors are looking for in your response
Evidence of how you, and if relevant your team, have:
- the relevant experience (appropriate to career stage) to deliver the proposed work
- the right balance of skills and expertise to cover the proposed work
- the appropriate leadership and management skills to deliver the work and your approach to develop others
- contributed to developing a positive research environment and wider community
You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.
The word limit for this section is 1,650 words: 1,150 words to be used for R4RI modules (including references) and, if necessary, a further 500 words for Additions.
Use the Résumé for Research and Innovation (R4RI) format to showcase the range of relevant skills you and, if relevant, your team (project and project co-leads, researchers, technicians, specialists, partners and so on) have and how this will help deliver the proposed work. You can include individuals’ specific achievements but only choose past contributions that best evidence their ability to deliver this work.
Complete this section using the R4RI module headings listed. Use each heading once and include a response for the whole team, see the UKRI guidance on R4RI. You should consider how to balance your answer, and emphasise where appropriate the key skills each team member brings:
- contributions to the generation of new ideas, tools, methodologies, or knowledge
- the development of others and maintenance of effective working relationships
- contributions to the wider research and innovation community
- contributions to broader research or innovation users and audiences and towards wider societal benefit, including public partnerships
Additions
Provide any further details relevant to your application. This section is optional and can be up to 500 words. You should not use it to describe additional skills, experiences, or outputs, but you can use it to describe any factors that provide context for the rest of your R4RI (for example, details of career breaks if you wish to disclose them).
Complete this as a narrative. Do not format it like a CV.
References may be included within this section.
The roles in funding applications policy has descriptions of the different project roles.
Project partners
Add details about any project partners contributions. If there are no project partners, you can indicate this on the Funding Service.
A project partner is a collaborating person or organisation who will have an integral role in your proposed research. Their involvement may include direct (cash) and or indirect (in-kind) contributions such as expertise, staff time, use of facilities or recruitment of research participants. Project partners may be in industry, academia, third sector or government organisations in the UK or overseas, including partners based in the EU.
A project partner is not anyone in your core team or anyone from your organisation or any of the other organisations represented by core team members.
Add the following project partner details:
- the organisation name (searchable via a drop-down list or enter the organisation’s details manually, as applicable)
- the project partner contact name and email address
- the type of contribution (direct or in-direct) and its monetary value
If a detail is entered incorrectly and you have saved the entry, remove the specific project partner record and re-add it with the correct information.
If there are specific circumstances where project partners do require funding for minor costs such as travel and subsistence, these project partner costs should be claimed and justified within the resources and costs section of your application.
Important information
If you are adding a project partner to this section, you must ensure they provide you with a letter or email of support and you upload it to ‘Project partners: letters or emails of support’.
If your project partners are from industry or a company, you must also complete the ‘Industry Collaboration Framework (ICF)’ section.
Project partners: letters (or emails) of support
Word limit: 10
Upload a single PDF containing the letters or emails of support from each partner you named in the ‘Project partners’ section. These should be uploaded in English or Welsh only.
What the assessors are looking for in your response
If you do not have any project partners, you will be able to indicate this in the Funding Service.
What supporting statements we are looking for
We are looking for you to provide letters or emails of support from all your identified project partners.
What we are not looking for
We do not want any other letters (or emails) of support, from people who are not your identified project partners, such as those simply expressing general support for your project. If these are included by you, they will be ignored by us and will not be used in the assessment process.
Important information
You should only provide letters or emails of support from people you have identified in the project partner section of your application, who will have an integral role in your proposed research.
What each project partner letter or email of support must include
Each project partner letter or email you provide should:
- include the name of the project partner organisation and contact information
- explain the project partners’ commitment to the project
- explain the value, relevance, and possible benefits of the proposed work, to them
- describe any additional value they will bring to the project
- not exceed two sides of A4 per project partner
Project partner letters and emails of support are not required to be on headed paper or include handwritten signatures (electronic signatures are acceptable).
The Funding Service will provide document upload details when you apply.
Project partners from industry or a company
Industry or company project partners are required to download and complete the industry or company letter of support template. You must also complete the ‘Industry Collaboration Framework (ICF)’ section. Find out more about ICF.
Project partners responsible for recruiting research participants or providing human tissue or samples
If the project partner is responsible for the recruitment of people as research participants or providing human tissue, their letter or email of support should include:
- agreement that the project partner will recruit the participants or provide tissue
- confirmation that what is being supplied is suitable for the proposed work
- confirmation that the quantity of tissue being supplied is suitable, but not excessive for achieving meaningful results (if applicable)
Agreement with your project partners
Ensure you have prior agreement from project partners so that, if you are offered funding, they will support your project as indicated in the ‘Project partners’ section.
For audit purposes, UKRI requires formal collaboration agreements to be put in place if an award is made.
Industry Collaboration Framework (ICF)
Word limit: 1,500
Does your application include collaboration with industry or company project partners?
What the assessors are looking for in your response
The assessors are looking for you to confirm if your proposed work involves collaboration with an industry or company project partner. If it does, you will need to follow the MRC industry collaboration framework (ICF).
By ‘industry or company’ we mean an enterprise that puts or has intention to put goods or services on a market.
For guidance to assist your decision if your proposed work requires you to follow ICF, you should explore the ICF decision tree and find out more about ICF which includes:
- collaboration agreements
- definitions of basic or applied research
- internationally based companies
- subsidy control
- intellectual property (IP) arrangements
- fully flexible and gated contributions
- the ICF assessment criteria
Enter ‘Yes’ in the text box if you have industry or company project partners and you are likely to follow ICF. You should also confirm your answers to the ICF questions one to nine in the text box for each ICF project partner.
Contact us if you are unsure if your application should follow ICF.
In addition to the project partner information completed in the previous section, the assessors are looking for information relating to the nature, goals and conditions of the collaboration and any restrictions or rights to the project results that could be claimed by the industry or company project partner.
Confirm your answers to the ICF questions in the text box, repeat this process for each ICF project partner:
- Name the industry or company project partner considered under ICF.
- Indicate whether your application is basic research or applied research.
- Explain why, in the absence of the requested UKRI funding, the collaboration and the planned research could not be undertaken.
- State whether your application is under the category of fully flexible contribution or gated contribution (based on the IP sharing arrangements with the industry or company partner).
- Outline the pre-existing IP (‘background IP’) that each partner, including the academic partner, will bring to the collaborative research project and the terms under which partners may access these assets.
- Outline the IP that is expected to be developed during the collaborative research project (‘foreground IP’) and briefly outline how it will be managed, including:
- who will own this IP
- what rights industry or company partners will have to use academically-generated foreground IP during and after the research project, for internal research and development or for commercial purposes
- any rights of the academic partner to commercialise the foreground IP, including foreground IP generated by industry or company partners
- Outline any restrictions to dissemination of the project results, including the rights of the industry or company partner to:
- review, approve or delay publications (including the time period associated with such rights)
- request or require the removal of any information
- Declare any conflicts of interest held by the applicants in relation to the industry or company project partners and describe how they will be managed.
- Justify collaborating with an overseas industry or company under ICF (if applicable).
Failure to provide the information requested for industry or company partners under ICF could result in your application being rejected.
You are recommended to discuss the goals and conditions of any collaboration with an industry or company with your technology transfer or contracts office before applying.
For audit purposes, UKRI requires formal collaboration agreements to be put in place if an award is made. You must provide us with a copy of the collaboration agreement, signed by all partners, before an ICF award starts.
If this does not apply to your proposed work, you will be able to indicate this in the Funding Service.
Trusted Research and Innovation (TR&I)
Word limit: 100
Does the proposed work involve international collaboration in a sensitive research or technology area?
What the assessors are looking for in your response
Demonstrate how your proposed international collaboration relates to Trusted Research and Innovation, including:
If your proposed work does not involve international collaboration, you will be able to indicate this in the Funding Service.
We may contact you following submission of your application to provide additional information about how your proposed project will comply with our approach and expectation towards TR&I, identifying potential risks and the relevant controls you will put in place to help manage these risks.
Facilities
Word limit: 250
Does your proposed research require the support and use of a facility?
What the assessors are looking for in your response
If you will need to use a facility, follow your proposed facility’s normal access request procedures. Ensure you have prior agreement so that if you are offered funding, they will support the use of their facility on your project.
For each requested facility you will need to provide the:
- name of facility, copied and pasted from the facility information list (DOCX, 42KB)
- proposed usage or costs, or costs per unit where indicated on the facility information list
- confirmation you have their agreement where required
Facilities should only be named if they are on the facility information list above. If you will not need to use a facility, you will be able to indicate this in the Funding Service.
Ethics and responsible research and innovation (RRI)
Word limit: 500
What are the ethical or RRI implications and issues relating to the proposed work? If you do not think that the proposed work raises any ethical or RRI issues, explain why.
What the assessors are looking for in your response
Demonstrate that you have identified and evaluated:
- the relevant ethical or responsible research and innovation considerations
- how you will manage these considerations
Consider the MRC guidance on ethics and approvals.
You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.
Genetic and biological risk
Word limit: 700
Does your proposed research involve any genetic or biological risk?
What the assessors are looking for in your response
In respect of animals, plants or microbes, are you proposing to:
- use genetic modification as an experimental tool, like studying gene function in a genetically modified organism
- release genetically modified organisms
- ultimately develop commercial and industrial genetically modified outcomes
If yes, provide the name of any required approving body and state if approval is already in place. If it is not, provide an indicative timeframe for obtaining the required approval.
Identify the organism or organisms as a plant, animal or microbe and specify the species and which of the three categories the research relates to.
Identify the genetic and biological risks resulting from the proposed research, their implications, and any mitigation you plan on taking. Assessors will want to know you have considered the risks and their implications to justify that any identified risks do not outweigh any benefits of the proposed research.
If this does not apply to your proposed work, you will be able to indicate this in the Funding Service.
Research involving the use of animals
Word limit: 10
Does your proposed research involve the use of vertebrate animals or other organisms covered by the Animals Scientific Procedures Act?
What the assessors are looking for in your response
If you are proposing research that requires using animals, download and complete the Animals Scientific Procedures Act template (DOCX, 74KB), which contains all the questions relating to research using vertebrate animals or other Animals (Scientific Procedures) Act 1986 regulated organisms.
Save it as a PDF. The Funding Service will provide document upload details when you apply.
If this does not apply to your proposed work, you will be able to indicate this in the Funding Service.
Conducting research with animals overseas
Word limit: 700
Will any of the proposed animal research be conducted overseas?
What the assessors are looking for in your response
If you are proposing to conduct overseas research, it must be conducted in accordance with welfare standards consistent with those in the UK, as in Responsibility in the use of animals in bioscience research. Ensure all named applicants in the UK and overseas are aware of this requirement.
If your application proposes animal research to be conducted overseas, you must provide a statement in the text box. Depending on the species involved, you may also need to upload a completed template for each species listed.
Statement
Provide a statement to confirm that:
- all named applicants are aware of the requirements and have agreed to abide by them
- this overseas research will be conducted in accordance with welfare standards consistent with the principles of UK legislation
- the expectation set out in Responsibility in the use of animals in bioscience research will be applied and maintained
- appropriate national and institutional approvals are in place
Templates
Overseas studies proposing to use non-human primates, cats, dogs, equines or pigs will be assessed during NC3Rs review of research applications. Provide the required information by completing the template from the question ‘Research involving the use of animals’.
For studies involving other species, such as:
- rodents
- rabbits
- sheep
- goats
- pigs
- cattle
- xenopus laevis and xenopus tropicalis
- zebrafish
Select, download, and complete the relevant Word checklist or checklists by exploring NC3Rs checklist for the use of animals overseas.
Save your completed template as a PDF and upload to the Funding Service. If you use more than one checklist template, save it as a single PDF.
The Funding Service will provide document upload details when you apply.
If conducting research with animals overseas does not apply to your proposed work, you will be able to indicate this in the Funding Service.
Research involving human participation
Word limit: 700
Will the project involve the use of human subjects or their personal information?
What the assessors are looking for in your response
If you are proposing research that requires the involvement of human subjects, provide the name of any required approving body and whether approval is already in place.
Justify the number and the diversity of the participants involved, as well as any procedures.
Provide details of any areas of substantial or moderate severity of impact.
If this does not apply to your proposed work, you will be able to indicate this in the Funding Service.
Research involving human tissues or biological samples
Word limit: 700
Does your proposed research involve the use of human tissues, or biological samples?
What the assessors are looking for in your response
If you are proposing work that involves human tissues or biological samples, provide the name of any required approving body and whether approval is already in place.
Justify the use of human tissue or biological samples specifying the nature and quantity of the material to be used and its source.
If this does not apply to your proposed work, you will be able to indicate this in the Funding Service.
Resources and cost justification
Word limit: 1,000
What will you need to deliver your proposed work and how much will it cost?
What the assessors are looking for in your response
Justify the application’s more costly resources, in particular:
- project staff
- significant travel for field work or collaboration (but not regular travel between collaborating organisations or to conferences)
- any equipment that will cost more than £25,000
- any consumables beyond typical requirements, or that are required in exceptional quantities
- all facilities and infrastructure costs
- all resources that have been costed as ‘Exceptions’
- support for public and patient involvement and engagement. Payments to public partners can be included under the exceptions fund heading
- support for preserving, long-term storage, or sharing of data
- support for international co-leads, demonstrating this is within the 30% costs cap for co-leads from high income countries, India and China. There is no cap on costs requested for international applicants from DAC list countries
- NHS research costs, when they are associated with NHS studies
- animal costs, such as numbers that need to be bred or maintained and to maintain high welfare standards
Justify why the partnership cannot be supported in any other way than the MRC funding requested.
Justify why each applicant is necessary for the partnership, including their level of time commitment.
You can request costs associated with reasonable adjustments where they increase as a direct result of working on the project. For further information see Disability and accessibility support for UKRI applicants and grant holders.
Assessors are not looking for detailed costs or a line-by-line breakdown of all project resources. Overall, they want you to demonstrate how the resources you anticipate needing for your proposed work:
- are comprehensive, appropriate, and justified
- represent the optimal use of resources to achieve the intended outcomes
- maximise potential outcomes and impacts
Clinical research using NHS resources
Word limit: 250
Are you applying to do clinical research in the UK?
What the assessors are looking for in your response
Researchers applying to do clinical research in the NHS, public health or social care usually need to complete a Schedule of Events Cost Attribution Tool (SoECAT).
We request the SoECAT because we want to know that you have taken the appropriate steps to request National institute for Health and Care Research (NIHR) support and for the full costs of your research to be attributed, calculated and paid.
We want to see the expected total resources required for your project to consider if these are appropriate.
Enter ‘Yes’ and complete and upload a SoECAT if you are applying for clinical research and:
- you will carry out your research in the UK
- your research will use NHS resources
- the research requires approval by Health Research Authority (England) or its equivalents in Northern Ireland, Scotland or Wales
- you will need support from the NIHR Research Delivery Network, this may include studies in a social care or public health setting
It is important to complete a SoECAT to be eligible for NIHR support. You must complete a SoECAT even if you do not think your clinical research will involve excess treatment costs (ETCs).
See MRC guidance on who needs to complete a SoECAT.
How to complete a SoECAT
SoECAT guidance can be found on the NIHR website.
These are the steps you need to take:
- Contact an attributing the costs of health and social care Research & Development (AcoRD) specialist as early as possible in the application process
- Complete an online SoECAT. Excel versions of the form have been discontinued. If you do not have an account for NIHR’s Central Portfolio Management System (CPMS) you will need create and activate one. See the NIHR user guide for instructions
- Request authorisation of your SoECAT
- Once authorised extract the ‘study information’ and the ‘summary’ page from the ‘Funder Export’, combine them as a single PDF and upload it to your application.
Applications that require a SoECAT but have not uploaded the SoECAT funder export study information and summary may be rejected.
Ensure the AcoRD specialists name and date are included within the uploaded summary page. The SoECAT is invalid without this information.
Contact us if you have questions about the UKRI aspects of this process or have concerns that your SoECAT may not be authorised in time for the application closing date.
If this does not apply to your proposed work, you will be able to indicate this in the Funding Service.
Related applications
Word limit: 500
Is this application related to another application to MRC or other funding organisation?
What the assessors are looking for in your response
If your application is not related to another, you will be able to indicate this in the Funding Service.
If yes, state your previous reference number and explain how this new application is related to the other application.
If the related application was submitted to another funder, you should identify the name of the funder and when you applied.
If this is a resubmission, describe how it differs from the previous application and how feedback on the previous application has been considered and acted on.
International agreements
Word limit: 50
Is your application using an international agreement?
What assessors and looking for in your response
If not, enter ‘N/A’ in the text box.
If your application is using an international agreement, identify the agreement concerned by answering ‘Yes’ followed by ‘FAPESP’ or ‘FNR’ or ‘RCN’:
- lead agency agreement with Luxembourg (FNR)
- lead agency agreement with Sao Paulo Research Foundation (FAPESP)
- Collaborate with researchers in Norway (RCN)
Lead agency agreements
For applications using a lead agency agreement the assessors are looking for you to create and upload the required lead agency documents, to support your application. You must complete all the relevant documentation and attach it to this application as a single PDF. This is not required for applications using the Collaborate with researchers in Norway agreement.
FAPESP
FAPESP applicants must complete the FAPESP-specific forms.
Documents and guidance are available on the FAPESP website, including a FAPESP:
- consolidated budget form
- letter of eligibility
FNR
FNR applicants should complete the FNR-specific forms.
Documents and guidance are available on the FNR website, including:
- INTER budget sheet
- INTER budget justification
- INTER budget plan
- FNR eligibility letter of support
You must also complete the ‘Project partners’ section, with information about the international research partner, including:
- international lead applicant contact name and organisation details
- contribution from the international funder (FAPESP or FNR)
Include the experience, skills and contributions of your international research partners in the response to ‘Applicant and team capability to deliver’.
You should ensure that you have read and understood the specific requirements for the lead agency agreement you are applying to, especially for costing the applications. Failure to comply with the specific guidance may result in the rejection of your application.
On receipt of your application, we will provide the international funder (FAPESP or FNR) with a copy to complete eligibility checks and provide names of expert reviewers.
For general FAPESP guidance please see the FAPESP website.
For general FNR guidance please see the FNR website.
Collaborate with researchers in Norway
There are no additional documents, complete the application as normal requesting all the required resources and costs and include the Norway-based researcher as a project co-lead (international).
For further guidance, including the costs the MRC will cover, please see the funding opportunity page.
